Báo cáo hóa học: "A randomized phase II trial of mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with 13-cis retinoic acid, interferon and paclitaxel in patients with metastatic castrate-resistant prostate cancer: ECOG 3899" pot
... phase II trial of
mitoxantrone, estramustine and vinorelbine or bcl-2 modulation with
13-cis retinoic acid, interferon and paclitaxel in patients with metastatic
castrate-resistant prostate cancer: ... 8 of 9
RESEA R C H Open Access
A randomized phase II trial of mitoxantrone,
estramustine and vinorelbine or bcl-2 modu...
... lower disinhibition score, indicating an
increase likelihood to overeat in the presence of disinhib-
itors. This was an unexpected finding and may indicate
that there are still certain triggers ... have
been influenced by all study patients participating in an
orientation meeting, in addition to meeting with the prin-
cipal investigator at the 3 measurement time points. It
may b...
... perception-action coupling and func-
tional motor tasks: perception of environmental con-
straints, motor planning and execution, and corrective
monitoring of performance including explicit feedback
[10]). ... compo-
nent in the activities of daily livings (ADLs) (e.g. eating,
drinking, grooming) which involve arm movements.
Many studies have examined point-to-point reaching in...
... randomized, controlled Phase III trial evaluating the effect
of adalimumab in patients with psoriasis (N = 1,205). Patients with moderate to severe psoriasis were randomized in a 2:1 ratio
to adalimumab ... NH, and MKW designed and interpreted the
analysis of health-related quality of life data. AM and SF
assisted Abbott Laboratories with the original Phase...
...
The toxicity in treatment with Cisplatin consisted of nausea and vomiting in 38 patients (62.3% of
Cisplatin-treated patients) ; this was WHO grade 3 in 17 pts (27.9%) and grade 4 in 10 pts (16.4%); ... Wiltshaw E, Evans B, Rustin G. A prospective randomized trial comparing high-dose cisplatin with low-
dose cisplatin and chlorambucil in advanced ovarian carci...
... measuring tumor
growth potential [25], with systemic injection for measur-
ing invasive and metastatic growth potential in EML
assays [51], or with orthotopic administration of tumor
cells for measuring ... levels of cytokines and growth factors
in GBM-M2 cells
The expression of a number of factors and interleukins is
increased in patient GBM and is associated w...
... NCI/FDA/iSBTc
sponsored workshop tied to the annual meeting of the iSBTc to be held in Washington DC in the
Fall of 2009. This foreword provides an overview of the task force and invites feedback ... quality of the material will remain a primary
focus of the working group, the need for platform stand-
ardization or, at least comparability of results to facilitate
inter -tri...
... Binding of β2m or a specific antibody
to open forms of HLA class I promoted phosphorylation of ERK1/2 in medulloblastoma cell line
with high levels, but not in the cell line with low levels of ... conformation). Binding of extracellular β
2
m to open conformer releases the receptor, enabling full blown
signaling indicated by increased phosphorylation (P) of intracellula...
... regeneration.
Materials and methods
Testing were performed in the quality control laboratory
of the cell therapy unit of the Cardiocentro Ticino. The
Laboratory is authorized and regularly inspected by ... that
could originate from the starting or raw materials or
adventitiously introduced during the manufacturing proc-
ess. In any case, a thorough testing must be performed at...
... the
SNP information of the subjects). Given a training set of
instance-label pairs, the SVM algorithm maps the training
vectors into a higher dimensional space by employing a
kernel function and ... months of persistent
fatigue resulting in substantial reduction in the person's
level of activity [2-4]. Furthermore, in CFS, four or more
of the following symptoms are pr...