... GM and TRZ: contrib-
uted to study design and concept and writing and editing of the manuscript.
VT: contributed to the study design and concept, writing and editing of the
manuscript and provided ... manuscript. TZ provided samples,
supervised in study design, and was involved in drafting
the manuscript. VT carried out the initial conception and
design of t...
... ASA and clopidogrel combined compared with either drug alone.
Conclusion: The indirect pharmacodynamic measures of the effects of ASA and clopidogrel might be used together with
ADP-induced activation ... ristocetin-induced adhesion appears to be
dependent on GPIb-IX-V and vWf [23].
We found that platelet adhesion to albumin, collagen and
fibrinogen induced by ADP was suppress...
... significant difference was found
between the low-dose and medium-dose groups
(P > 0.05).
Increased mRNA level of TFAM induced by
D- Gal
To understand whether increased mtDNA proliferation
induced by d ... partially
explain the increased mutation load in the inner ear.
In our study, increases in TFAM expression and dele-
tion mutation load were demonstrated in the inne...
... pla-
cebo and 54 dosed) individuals were assessed at all time
points except day 3. Mean, standard deviation % CV and
standard error for the data grouped across all placebos
and placebos + pre-dose ... experiments and drafted the
manuscript. AL carried out the assay in the clinical trials.
MG aided in the design of the experiments and review of
the manuscript. All a...
... par-
ticipated in sequence alignment and performed the statis-
tical analyses. HY and DH participated in the design of the
study. PD conceived the study, participated in its design
and coordination, and ... results in a premature stop codon
and a truncated Cx31 protein. In addition, 24_49ins26bp
and N166S were detected only in patients with hearing
impairme...
... analysis. DL, YS, and JD
interpreted the data and wrote the manuscript. All authors read and
approved the final manuscript.
Competing interests
DL, YS, KV, MS, and VB, and JDS have no competing interests. ... S110 into the deoxycytosine analog decitabine that binds and depletes DNA.
Conclusion: S110 is rapidly converted into decitabine, hypomethylates DNA, and induce s H...
... disease
stage and the occurrence of infections [3]. Accordingly,
in all our patients but one, the IgG and IgA serum levels
were within the normal range found in controls, and
this was expected, considering ... recruited the patients. MC, CG, CZ and CL performed the
laboratory work for this study. LI, MM, LC and GR wrote the manuscript and
participated to the...
... collected the date,
performed statistical analysis and drafted the manuscript.
AKW, BRH and AHH participated in the design and
revised the manuscript critically. TWL participated in the
design, conducted ... deaths, and the associated health costs will
increase during the next decade. In addition to the social
strain, COPD also influences the patients& apos; s...
... patients with type 2 diabetes in primary care
regarding the common comorbid conditions hyperten-
sion and osteoarthritis and therefore contributes to a bet-
ter understanding of diabetic patients. The ... within further research.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
AM designed and conducted the study...
... performed the statistical analysis and drafted the
manuscript. All authors read and approved the final man-
uscript.
Acknowledgements
The SHIELD Study Group includes the following individuals: Harold ... and associates and
Sitoh and colleagues [18,19], an ordinal variable for the
EQ- 5D index was created by categorizing the continuous
variable into 4 levels, and an...