... p40
0
1
2
3
4
5
0.00
0.01
0.02
AST
Control
AST/Mat
Mat
AST
Control
AST/Mat
Mat
AST
Control
AST/Mat
Mat
Relative expressionRelative expression
AST/Mat
AST/Mat
AST/Mat
AST
Control
Mat
AST
Control
Mat
AST
Control
Mat
0.000
0.005
0.010
0.015
0.8
1.0
Journal ... grants from the Compagnia di San Paolo,
the Comitato Interministeriale per la Programmazione Economica (CIPE),
the AIRC (Associazio...
... display cellular char-
acteristics of senescence. J Vasc Surg 1998, 28:876-883.
22. Hasan A, Murata H, Falabella A, Ochoa S, Zhou L, Badiavas E, Falanga
V: Dermal fibroblasts from venous ulcers are ... Gen-
tamicin (50 μg/ml) was used. The flask was inverted and
4 ml additional medium was added. This facilitated the
rapid attachment of the cells from the biopsy to the flask.
After...
... in
humans and mice are a good example of how studies in
animal models and humans may go hand in hand [2]. In
fact, animal studies continue as a basis for important
advances because they have allowed the ... fashion.
Statistical analysis
Data from the animal experiments were analyzed by one-
way analysis of variance for analyses of statistical signifi-
cance, with p < 0.05 indicat...
... showed that RES induces apoptosis
through a caspase-dependent pathway. Therefore, the
activity of caspase 3, a major component of the caspase
pathways, was analyzed. In addition, the role ERKs and
p38 ... 68:36-42.
14. Tyagi A, Singh RP, Agarwal C, Siriwardana S, Sclafani RA, Agarwal R:
Resveratrol causes Cdc2-tyr15 phosphorylation via ATM/
ATR-Chk1/2-Cdc25C pathway as a centra...
... machefinehaifatto@libero.it; Alfonso Campanile - facampanile@libero.it; Gennaro Galasso - gengalas@unina.it;
Barbara Ziaco - barbara.ziaco@unina.it; Giovanna Giuseppina Altobelli - ggaltobe@unina.it; Vincenzo ... were evaluated by analy-
sis of variance (ANOVA).
Statistical Analysis
All data are presented as the mean value ± SEM. Statistical
differences were determined by one-way or two-...
... usually accompanied by ascites
[3]. Massive ascites and the associated abdominal disten-
tion can cause anorexia, nausea, vomiting and respiratory
difficulties, affecting the patient's quality ... assessed. Luciferase activity was measured
using the Promega kit 'Luciferase Assay System& apos; (E-1500;
Promega, Madison, USA). Light output was detected using
a Lumac Biocounte...
... disease-focused biobanks. The latter include
informal biobanks associated with small and large
research studies, basic research disease-affiliated banks,
and clinical trial-biobanks. An escalating demand for
biospecimens ... BC, Canada,
7
Department of Pathology, Vancouver General Hospital, Vancouver,
BC, Canada Canada,
8
Centre for Translational and Applied Genomics, Vancouver, BC, Cana...
... gastrointestinal and pancre-
atic carcinomas. Virchows Arch 2001, 439:109-117.
9. Koga T, Tokunaga E, Sumiyoshi Y, Oki E, Oda S, Takahashi I, Kakeji Y,
Baba H, Maehara Y: Detection of circulating gastric ... metastatic niche: adapting the foreign
soil. Nat Rev Cancer 2009, 9:285-293.
22. Hiraiwa K, Takeuchi H, Hasegawa H, Saikawa Y, Suda K, Ando T,
Kumagai K, Irino T, Yoshikawa T, Matsuda S...
... design, coordination, and data
interpretation and drafted the manuscript. All authors read and approved
the final manuscript.
Competing interests
The authors declare that they have no competing ... following thermal ablation of the p rimary tumor.
On the other hand, the anti-tumor immune response
reported in previous studies was not strong enough to
achieve a therapeutic gain....
... 5-FU/leucovorin,
irinotecan, oxal iplatin, and capecitabine, and the role of
targeted agents such as cetuximab and bevacizumab.
The platinum-based chemotherapy drugs cisplatin,
carboplatin, and oxaliplatin are among ... Fernandez-Garcia B, Vaque JP, Herreros-Villanueva M, Marques-Garcia F,
Castrillo F, Fernandez-Medarde A, Leon J, Marin MC: p73 cooperates with
Ras in the activation o...