... that the EVH1, Pro-rich and EVH2 domains all have the potential to function in protein binding. The presentstudy revealed that the EVH2 domain is the RAD51-binding domain. Minimal RAD51 binding ... domainbinds to proteins containing the consensus sequenceD ⁄ E FPPPPXD ⁄ E [21–23]. The Pro-rich domain alsobinds to profilin and proteins containing the SH3 andWW domains [17,24–26]. These ... process, the ENA ⁄ VASP family proteins bind to both the barbed end and sides of actin filaments [15–18]. Theseactin-binding activities are conserved in the EVH2domain [19,20]. On the other hand, the...