... role in the failure of ischemic wound healing, while antioxidants partly improve the healing in ischemic skin wounds (60). Oxygen free radicals mediate the inhibition of wound healing following ... stress (67). Inter-ruption of the overproduction of superoxide by the mitochondrial electron transport chain would nor-malize the pathways involved in the development of the oxidative ... associated in humans with reduced intracellular antioxidant (11). Interestingly, antioxidants improve insulin sensitivity and help in wound healing (16,17). Along with others, the investigators...