... hsumi@bioreg.kyushu-u.ac.jp(Received 31 May 2006, accepted 12 June2006)doi :10 .11 11/ j .17 42-4658.2006.053 71. xActivation of the superoxide-producing NADPH oxidase Nox1 requiresboth the organizer protein Noxo1 and the activator ... inregulation of Nox3, the role of the PX domain in Nox3activity remains unknown.In the process of cloning of human Noxo1, somespliced transcripts of the NOXO1 gene have beenidentified [15 ,17 19 ]. They ... (AF532985), Noxo1a(AY255768 and AF532983), and Noxo1d (AY1 913 59). On the basis of the sequence of splice variants, we synthesized the full-length Noxo1b, Noxo1c, Noxo1a, and Noxo1d byPCR-mediated...