contact dermatitis 4th ed - p frosch, et al , (springer, 2006)

... spontaneously, some act as prohaptens and may need activation,e.g ., by light- or enzyme-in- duced metabolic conversion,or oxidation [14].A pro- totype prohapten is p- phenylenediamine, which needs to ... with naive T lymphocytes, recogniz- ing altered self [4 8, 7 1, 72]. í Professional antigen-presenting cells of the epidermis, called Langerhans cells, take up penetrated allergens...

... Johansen et al. (eds. ), Contact Dermatitis, DOI: 10.1007/97 8-3 -6 4 2-0 382 7-3 _ 2, © Springer-Verlag Berlin Heidelberg 2011 Abbreviations AFMU 5-acetylamino-6-formylamino- 3-methyluracil ACD Allergic contact ... time, the members of the group were: Andersen, Benezra, Brandao, Bruynzeel, Burrows, Camarasa, Ducombs, Frosch, Goossens, Hannuksela, Lachapelle, Lahti...