... international normalized ratio (INR), and a liver panel. Although the serum aminotransferase level correlates poorly with liver histology, the ratio of aspartate aminotransferase (AST) to alanine ... is a common cause of chronic liver disease and hepatocellular carcinoma. HCV antibody and HCV RNA testing are available diagnostic studies that offer high degree of accuracy. Current standard ... infection. Am J Gastroenterol 1998;93(1):44-8. 29. Giannini E, Risso D, Botta F, et al. Validity and clinical utility of the aspartate aminotransferase-alanine aminotransferase ratio in assessing...