... chain reaction (PCR), “real-time” PCR or TMA [5]. HCV RNA is extracted and reverse transcribed into a double stranded complementary DNA (cDNA), which is subsequently processed into a cyclic enzymatic ... the exact prevalence of which is unknown. Int. J. Med. Sci. 2006, 3 37Chronic hepatitis C In patients with clinical or biological signs of chronic liver disease, chronic hepatitis C is certain ... France. Tel : +3 3-1 -4 98 1-2 827, Fax : +3 3-1 -4 98 1-4 831. E-mail : jean-michel.pawlotsky@hmn.aphp.fr Received: 2006.01.12; Accepted: 2006.03.15; Published: 2006.04.01 The use of serological and...