Báo cáo Y học: Investigations into the mechanisms used by the C-terminal anchors of Escherichia coli penicillin-binding proteins 4, 5, 6 and 6b for membrane interaction ppt
Báo cáo Y học: Investigations into the mechanisms used by the C-terminal anchors of Escherichia coli penicillin-binding proteins 4, 5, 6 and 6b for membrane interaction ppt
... Investigations into the mechanisms used by the C-terminal anchors of Escherichia coli penicillin-binding proteins 4, 5, 6 and 6b for membrane interaction Frederick Harris1, Klaus Brandenburg2, ... have used theoretical analysis toinvestigate the potential of the PBP4, PBP5, PBP6 and PBP6b C-terminal regions for membrane interaction and based on these analyses, it would appear that these C-terminal ... Nonethe-less, the membrane interactive mechanisms utilized by the C-terminal anchors of PBP4 and PBP6b show differences tothose utilized by PBP5 and PBP6. Here, hydrophobicmoment-based analyses...
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Tài liệu Báo cáo Y học: Insights into the reaction mechanism of Escherichia coli agmatinase by site-directed mutagenesis and molecular modelling ppt
... the sequences of 1CEV and 1RLA and pasted into the structural alignment. The alignment was then corrected by hand. Since the sequences of the two arginases and agmatinase greately differ in the ... arginase (yellow) and the modelled structure of E. coli agmatinase (blue). Note the shorter extension, in the case of E. coli agmatinase, of the loop indicated by the letter a.Fig. 5. Scheme of the ... the consequences of the Asp153fiAsn substitution, we used amodelled structure of the E. coli enzyme, constructed by using homology-modelling techniques and the 3D structure of the binuclear form of B. caldovelox...
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Báo cáo khoa học: Investigations into the ability of an oblique a-helical template to provide the basis for design of an antimicrobial anionic amphiphilic peptide pot
... deeply into the membranes hydrophobic core.To investigate further the mechanism of bacterial membrane interaction used by AP1, thermodynamicanalysis of compression isotherms for lipid monolayermimetics ... hypo-thesis of Tytler et al. [48], it may be that insertion of the inverted wedge shape formed by the AP1 a-helix into membranes of E. coli leads to the formation of nonbilayer structures and ... to the susceptibility of E. coli to the antimicrobial action of the peptide.Discussion The biological action of many pore-forming and lyticpeptides involves membrane destabilization by the...
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Báo cáo y học: "Technical Considerations in Decompressive Craniectomy in the Treatment of Traumatic Brain Injury"
... d b y loose closure of the dura and skin layers presum a b l y allows for expansion of the edematous brain into a durotomy “bag” under the loosely closed scalp without restriction by the ... meninges. The method using temporal fascia is similar to the one introduced by Yu et al.32 They separated the temporal deep fascia from the temporal muscle to the zygomatic arch, and then cut the ... vessels as they pass the edge of the dural window (the pillars were made of hemostastic sponge wrapped by absorbable thread), and then the superfi-cial vessels supporting the portion of brain...
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Báo cáo y học: "Elevated plasma homocysteine is positively associated with age independent of C677T mutation of the methylenetetrahydrofolate reductase gene in selected Egyptian subjects"
... Frequency of the MTHFR genotypes and the result of the Chi square testing in the different studied groups. Showing the frequency and the results of the cross tabulation of the T allele and the different ... 5-methyltetrahydrofolate as a carbon donor [6] . This donor is synthesized by the methylenetetrahydrofolate reductase (MTHFR) gene from 5,1 0-methylene-tetrahydrofolate [9,10]. Reduction in the ... affected by the number of the 67 7T alleles in the MTHFR gene, with the strongest response in 67 7T homozygotes [30]. On the other hand, the association between carotid and coronary artery disease...
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Báo cáo y học: "Introduction into Pathology of Ocular Zoonoses"
... infection, groups of tachycoites multiply rapidly within intracellular cysts. The im-mune response induces the formation of bradycoites tightly packed in larger cysts containing hundreds of organisms. ... than a century, the term zoonosis indicated any disorder due to infectious agents visible by microscope. Ironically, the first re-ports of cytomegaly were attributed to an infection by a novel ... However, with the advent of modern microbiolgy the understanding of zoonosis has changed completely. No later than 1958, the World Health Organization produced an official definition of Zoonosis...
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Tài liệu Báo cáo Y học: Soluble silk-like organic matrix in the nacreous layer of the bivalve Pinctada maxima A new insight in the biomineralization field pptx
... material [ 46] . The position of the amide I band, the major protein absorptionband, depends on the conformation of the polypeptidechain [47]. The presence of this amide I absorption band at 165 6 cm)1suggests ... reverse-phaseHPLC of their phenylisothiocarbamate derivatives [ 26] , asreported previously [20]. The serine, threonine and tyrosinecontents of the hydrolysates were corrected for destructionduring the hydrolysis ... composition was very similar to the WSM, and consequently the EDTA-IM. Hydroxyproline, hydroxy-lysine and phosphoserine were not detected in WSM, WIM,EDTA-SM and EDTA-IM. The comparison of the amino...
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Tài liệu Báo cáo Y học: BIGH3 (TGFBI) Arg124 mutations influence the amyloid conversion of related peptides in vitro Implications in the BIGH3-linked corneal dystrophies pptx
... decades of life and severely impair visualacuity in adulthood. Their therapy is restricted to keratopl-asty and phototherapeutic keratectomy by Excimer laser.Unfortunately, the benefits of these therapies ... configuration and to form amyloid. The CONH2-terminus of the peptides analyzed has an inhibitoryFig. 6. Secondary structure determination of the peptides by FT-IRspectroscopy in D2O. Spectrograms of ... degree of amyloid fibril formation.Cysteine has the capacity to form disulfide bonds. Asdisulfide bonding of the protein may participate in the appearance of aggregates and predispose to the formationof...
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Tài liệu Báo cáo Y học: Studies into factors contributing to substrate specificity of membrane-bound 3-ketoacyl-CoA synthases pot
... this yeast system and/ or the ability of the enzymes further down the metabolic pathway to use the products of the FAE1 KCS condensation activity. Indeed,in the S. cerevisiae strain used in these ... However, the results are reflective of the entireyeast metabolic pathways from the synthesis of 3-ketoacylCoAs by a condensing enzyme to the incorporation of fattyacids into lipids such as triacylglycerol ... Asimple enzymatic method for the preparation of radiolabelederucoyl-CoA and other long-chain fatty acyl-CoAs and theircharacterization by mass spectrometry. Anal. Biochem. 1 84, 311–3 16. 36. Evenson,...
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Báo cáo Y học: Probing intermolecular protein–protein interactions in the calcium-sensing receptor homodimer using bioluminescence resonance energy transfer (BRET) potx
... study is that the translation of agonist binding to the ATDs of the family C GPCRhomodimer into G-protein coupling of the 7TM)7TMmoiety is mediated by another mechanism than thatproposed by ... activity in the receptor [59], and the splice variants of mGluR1 and mGluR5 with long carboxytermini are constitutively active [60 ,61 ]. All these pheno-mena originate exclusively from the 7TM of the ... pRluc/GFP2(pBRET+) by the introduction of a Ser65 fi ThrmutationintheGFP2part of the plasmid. For the construction of the c-myc-CaR and HA-CaRconstructs, a MluI site was introduced after the signalpeptide...
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Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnbáo cáo khoa học y họcbáo cáo y tế học đườngmẫu báo cáo y tế học đườngbáo cáo y tế học đường cuối nămBáo cáo thực tập tại nhà thuốc tại Thành phố Hồ Chí Minh năm 2018chuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếThiết kế và chế tạo mô hình biến tần (inverter) cho máy điều hòa không khíKiểm sát việc giải quyết tố giác, tin báo về tội phạm và kiến nghị khởi tố theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn tỉnh Bình Định (Luận văn thạc sĩ)Quản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Tranh tụng tại phiên tòa hình sự sơ thẩm theo pháp luật tố tụng hình sự Việt Nam từ thực tiễn xét xử của các Tòa án quân sự Quân khu (Luận văn thạc sĩ)chuong 1 tong quan quan tri rui roTÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲ