... Italy2 Istituto per la Radioprotezione, ENEA, CR Casaccia, Roma, ItalyThe polyamines putrescine (Put), spermine (Spm) andspermidine (Spd) are aliphatic amines that are posi-tively charged under ... the pro-tein is shown in a ‘mesh’ representation.The backbone and the molecular surface ofnuclear domains A and B (see the text) are coloured green and blue, respectively. TheFAD cofactor ... N1-acetyl-transferase,vertebrate polyamine oxidase (PAO) (EC 1.5.3.11)and spermine oxidase (SMO) are involved in main-taining polyamine homeostasis in mammalian cells.The cytosolic Spd ⁄ Spm...