... with acommon ancestry, very similar tertiary structure andconserved catalytic machinery and reaction mechanism[79]. Here we propose that a clan of carbohydrate-binding modules contains CBM ... Minassian BA, Ianzano L, Meloche M, Andermann E,Rouleau GA, Delgado-Escueta AV & Scherer SW(2000) Mutation spectrum and predicted function oflaforin in Lafora’s progressive myoclonus epilepsy.Neurology ... functional, and evolutionary relationships.Proteins 29, 334–347.65 Williamson MP, Le Gal-Coeffet MF, Sorimachi K,Furniss CS, Archer DB & Williamson G (1997) Func-tion of conserved tryptophans...