... [26] for the numeration used in this article). This C-terminalfragment forms a globular domain both as part of the full- length sequence and in the isolated form, and there-fore constructs of ... 2009 FEBSTable 1. List of plasmids encoding the sequence of the mature cellular form of the prion protein from a variety of species and truncatedvariants thereof, and of human doppel. The protein ... have been used for NMR structure determina-tions with many of the species [7,9–14,19,20,23,24].Actually, structure determinations of the full- lengthprotein have been performed only for the PrPs...