Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1 1 to 1 6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx

Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1.1 to 1.6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx

Báo cáo khoa học: Molecular basis for substrate recognition and drug ˚ resistance from 1.1 to 1.6 A resolution crystal structures of HIV-1 protease mutants with substrate analogs pptx

... (3.7) 17 .1 (2 .6) 14 .1 (13 .8) 10 .4 (2.9) Data range for refinement (A ˚ ) 10 1. 54 10 1. 40 10 1. 10 10 1. 30 10 1. 60 10 1. 42 10 1. 38 10 1. 32 R work (%) 0 .12 0 .15 0 .13 0 .12 0 .15 0 .18 0 . 16 0 .13 R free (%) ... complexes with substrate analogs FEBS Journal 272 (2005) 5 265 –5277 ª 2005 FEBS 5277 Molecular basis for substrate recognition and...
Ngày tải lên : 30/03/2014, 20:20
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Báo cáo khoa học: Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase potx

Báo cáo khoa học: Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase potx

... chempbsa@savba.sk (Received 17 December 2 010 , revised 10 April 2 011 , accepted 13 April 2 011 ) doi :10 .11 11/ j .17 42- 465 8.2 011 .0 812 7.x Xylanase A from the phytopathogenic bacterium Erwinia chrysanthemi is classified as a glycoside ... of xylanase A ligand complex L ˇ . Urba ´ nikova ´ et al. 211 6 FEBS Journal 278 (2 011 ) 210 5– 211 6 Journal compilation ª 2 011...
Ngày tải lên : 22/03/2014, 16:20
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Báo cáo khoa học: Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases pptx

Báo cáo khoa học: Molecular basis for specificities of reactivating factors for adenosylcobalamin-dependent diol and glycerol dehydratases pptx

... Tsushima-naka, Okayama 700–8530, Japan Fax: + 81 86 2 518 264 Tel: + 81 86 2 518 194 E-mail: toraya@cc.okayama-u.ac.jp (Received 26 May 2007, revised 17 August 2007, accepted 29 August 2007) doi :10 .11 11/ j .17 42- 465 8.2007. 060 74.x Adenosylcobalamin-dependent ... Kajiura 1 , Koichi Mori 1 , Naoki Shibata 2 and Tetsuo Toraya 1 1 Department of Bioscience and Biotechnolo...
Ngày tải lên : 16/03/2014, 05:20
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Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

... Shimura Y, Ibuka A, Sakai H, Matsuzawa H, Sakano Y & Ohta T (19 95) Comparison of primary structures and substrate specificities of two pullulan-hydrolyzing a- amylases, TVA I and TVA II, from ... (2002) Crystal structures and structural com- parison of Thermoactinomyces vulgaris R-47 a- amylase I (TVAI) at 1. 6 A ˚ resolution and a- amylase II (TVAII...
Ngày tải lên : 19/02/2014, 00:20
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Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt

Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt

... P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 P2 1 2 1 2 1 Beamline X 11 X 11 X 11 X 11 X 11 ID14 -1 Unit cell: a ¼ 56. 86 A ˚ 56. 73 A ˚ 57.28 A ˚ 56. 80 A ˚ 56. 71 A ˚ 56. 78 A ˚ b ¼ 83. 21 A ˚ 83. 36 A ˚ 82 .68 A ˚ 83 .14 A ˚ 83.59 A ˚ 83.32 A ˚ c ......
Ngày tải lên : 23/03/2014, 11:20
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Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

Báo cáo khoa học: Molecular basis of the unusual catalytic preference for GDP/GTP in Entamoeba histolytica 3-phosphoglycerate kinase doc

... ± 16 0 0.38 15 6 ± 12 a 2244 ± 428 0.07 V 311 L 11 5 ± 9 18 9 ± 32 0. 61 120 ± 7 b 11 04 ± 62 0 .11 E309Q 300 ± 13 a 2 91 ± 66 1. 0 315 ± 15 2 13 13 ± 46 0.24 E309M 16 9 ± 24 15 3 ± 24 1. 1 18 2 ± 20 a 63 7 ± 15 2 b 0.29 Y239F ... 2 0 16 ± 210 0 .14 Y239F 10 00 ± 16 1 15 5 ± 13 6. 5 3 71 ± 55 269 3 ± 337 0 .14 V 311 L 969 ± 10 16 8 ± 23 5.8 562 ± 18 a...
Ngày tải lên : 16/03/2014, 01:20
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Báo cáo khoa học: Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D docx

Báo cáo khoa học: Structural basis for the changed substrate specificity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D docx

... 34.2 1 16. 5 7.2 · 10 6 1 dA N45D 11 9 3.8 1 1.83 15 378 6 N64D 3820 0.82 0.9 0.4 10 5 8 76 N45D ⁄ N64D a 3 16 6 1. 7 1 0.828 260 354 Wildtype b 225 42.7 1 20 .6 92000 1 dG N45D 412 2.7 1 1.3 315 5 7.3 N64D ... 0.5 0 .12 5.9 3898 N45D ⁄ N64D a 2004 0 .15 6 1 0.0 76 38 60 5 Wildtype b 66 5 31. 3 1 15 .1 23000 1 AZT N45D 11 .7 0. 06 1 0.03 2 564 1...
Ngày tải lên : 30/03/2014, 20:20
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Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc

Tài liệu Báo cáo khoa học: Molecular basis of glyphosate resistance – different approaches through protein engineering doc

... et al. 2 762 FEBS Journal 278 (2 011 ) 2753–2 766 ª 2 011 The Authors Journal compilation ª 2 011 FEBS catalytic base, and the 17 -fold drop in k cat for the Y 118 F mutant implicates Tyr 118 as a catalytic ... lyase pathway). Bottom: cleavage to yield AMPA and glyoxylate (the AMPA pathway), referred to as the GOX pathway. (B) Reaction catalyzed by GO on glyphosate, an alternativ...
Ngày tải lên : 14/02/2014, 14:20
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Tài liệu Báo cáo khoa học: Kinetic basis for linking the first two enzymes of chlorophyll biosynthesis doc

Tài liệu Báo cáo khoa học: Kinetic basis for linking the first two enzymes of chlorophyll biosynthesis doc

... Al Karadaghi S (20 01) Interplay between an AAA module and an integrin I domain may regulate the function of magnesium chelatase. J Mol Biol 311 , 11 1 12 2. 7 Reid JD, Siebert CA, Bullough PA & ... a higher available concentration of ChlM to bind other mole- cular species in the reaction. ChlH appears to enhance catalysis by accelerating the formation and decay of a ca...
Ngày tải lên : 20/02/2014, 02:21
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Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx

Báo cáo khoa học: Molecular basis of perinatal hypophosphatasia with tissue-nonspecific alkaline phosphatase bearing a conservative replacement of valine by alanine at position 406 Structural importance of the crown domain potx

... hypophosphatasia [1 4]. Perinatal and infantile forms of hypophosphata- sia are severe and are usually transmitted as a recessive trait, whereas the other three forms of hypophosphata- sia are mild and are ... revised 18 January 2008, accepted 19 March 2008) doi :10 .11 11/ j .17 42- 465 8.2008. 06 414 .x Hypophosphatasia, a congenital metabolic disease related to the tis...
Ngày tải lên : 07/03/2014, 05:20
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