... stimulated to divide in hyperglyce-mic medium. This initiated a protein kinase C (PKC)response, which led to the activation of HASs in intra-cellular compartments, including, most probably, ... and UDP-N-acetyl-glucosamine (UDP-glcNAc), and adds them alternatelyto the reducing end of the chain with release of theanchoring UDP. The elongating chain is extruded intothe extracellular ... MINIREVIEWHyaluronan matrices in pathobiological processesAimin Wang1, Carol de la Motte2, Mark Lauer1and Vincent Hascall11 Department of Biomedical Engineering, The Cleveland Clinic,...