... reported to upregulate the calci-neurin-dependent degradation of Yap1 p [29], the main transcription factor inducing gene expression in response to oxidative stress [19,20 ,30] . If the high cyto-solic ... When used, the calcium che-lator BAPTA was added to the cell suspension to the finalconcentration of 5 mm 1 min before application of the stress. To ensure that total reconstituted aequorin was ... 4A,B),indicating that, under lethal oxidative conditions, cellsrely mainly on internal Ca2+stores. Under the same stress conditions, yvc1D cells exhibited only faintCa2+-mediated luminescence...