... 2005 FEBS 2759 PKA independent and cell type specific activation of the expression of caudal homeobox gene Cdx-2 by cyclic AMPLiang Chen1,2, Peixiang Wang1,2, Cristiano F. Andrade1,2, Ian ... in the GLUTag cell line at 1, 2, 3, and 4 h.To investigate whether the activation of Cdx-2 pro-tein expression by forskolin ⁄ IBMX is caused by increasing intracellular levels of cAMP, the cell ... wefurther investigated the involvement of PKA in Cdx-2 expression. First, we compared the effects of PKAccotransfection on the expression of the Cdx-2 promo-ter vs. the proglucagon gene promoter....