Báo cáo khoa học: Bacterial b-peptidyl aminopeptidases with unique substrate specificities for b-oligopeptides and mixed b,a-oligopeptides pptx
Báo cáo khoa học: Bacterial b-peptidyl aminopeptidases with unique substrate specificities for b-oligopeptides and mixed b,a-oligopeptides pptx
... The Authors Journal compilation ª 2006 FEBS Bacterial b-peptidyl aminopeptidases with unique substrate specificities for b-oligopeptides and mixed b,a-oligopeptides Birgit Geueke1, Tobias Heck1, ... b-peptidyl aminopeptidases had 86% amino acid sequence iden-tity, hydrolyzed a variety of b-peptides and mixed b ⁄ a-peptides, and exhib-ited unique substrate specificities. The prerequisite for peptides ... analysis and biochemical characterizationof two b-peptidyl aminopeptidases. The enzymes havesimilar, but exceptional, substrate specificities. Theyhydrolyze a variety of b-oligopeptides and mixed...
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Báo cáo khoa học: "Fast Online Training with Frequency-Adaptive Learning Rates for Chinese Word Segmentation and New Word Detection" docx
... + 1 and i + 2• Character bigrams locating at positions i −2, i − 1, i and i + 1• Whether xj and xj+1are identical, for j = i −2, . . . , i + 1• Whether xj and xj+2are identical, for ... information ofxxx in edge features. For traditional implementationof CRF systems (e.g., the HCRF package), usuallythe edges features contain only the informationof yi−1 and yi, and without ... conditional random fields or latent variableconditional random fields, we simply use a singlefirst-order conditional random fields (CRFs) for the joint modeling. The semi-Markov CRFs and latent variable...
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Báo cáo khoa học: "Robust Dialog Management with N-best Hypotheses Using Dialog Examples and Agenda" pdf
... for Computational LinguisticsRobust Dialog Management with N-best Hypotheses Using Dialog Examples and AgendaCheongjae Lee, Sangkeun Jung and Gary Geunbae LeePohang University of Science and ... the recognition and understanding processes.However, it has been impossible to develop perfectASR and NLU modules because of noisy environ-ments and unexpected input. Therefore, the devel-opment ... languageunderstanding. These errors can cause the dialogsystem to misunderstand a user and in turn lead toan inappropriate response. To avoid these errors, abasic solution is to improve the accuracy and...
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Báo cáo khoa học: "Augmented Dependency Grammer: A Simple Interface between the Grammer Rule and the Knowledge" pptx
... morphological, syntactic, semantic, and conceptual information , and is used for describing the lexicon, semantic structure, conceptual structure and ADG rules. Feature is formalized as : Feature ~ ... Fillmore's case is not suitable for conceptual representaion primitive for a variety of syntactic and syntagmatic structures. On the other hand, syntax is a clue to understanding of sentences. Syntagmatic ... ADG and usual case semantics coincide with factual meaning CONCEPT SYMBOLs ADG semantics conceptual representation for both SENI and SEN2 Comprehension of constructing factual information...
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Báo cáo khoa học: "Learning How to Conjugate the Romanian Verb. Rules for Regular and Partially Irregular Verbs" docx
... between rules 1, 20, 22, and thesort lies in the suffix that is added to the stem for each verb form. They may share some suf-fixes, but not all and/ or not for the same person and number.1. no alternation; ... alternation: e→ea for the 3rd person singular and plural, t→t¸ for the 2nd person singular;”a des¸erta” (to empty);14. alternation:˘a→a for all the forms except the1st and 2nd person plural; ... d→z for the 2nd person singu-lar due to palatalization, along with ˘a→e; ”avedea” (to see), stem ends in ”d”;18. alternation:˘a→a for all forms except the 1st and 2nd person plural, d→z for...
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Báo cáo khoa học: A novel transmembrane topology of presenilin based on reconciling experimental and computational evidence pptx
... presenilin basedon reconciling experimental and computational evidenceAnna Henricson, Lukas Ka¨ll and Erik L. L. SonnhammerCenter for Genomics and Bioinformatics, Karolinska Institutet, Stockholm, ... proteinstudied and the nature of the reporter gene used, and therefore these studies must always be interpreted with caution. Antibody experiments on native proteins havebeen performed by Doan ... model with anextracytosolic N-terminus has also been proposed[19,20]. Other models that have been suggested include asix-TM model with cytosolic N- and C-termini [23], and a ‘seven-TM and one...
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Báo cáo khoa học: "Learning Stochastic OT Grammars: A Bayesian approach using Data Augmentation and Gibbs Sampling" pptx
... Yingnian Wu,Colin Wilson, and anonymous reviewers for their comments.• Each underlying form u corresponds to a setof candidates GEN(u). To obtain the unique surface form, the candidate set is successivelyfiltered ... σ2),C3∼ N(µ3, σ2), and 2 competing candidates for agiven input x:p(.) C1C2C3x ∼ y1.77 0 0 1x ∼ y2.23 1 1 0Table 1: A Stochastic OT grammar with 1 input and 2 outputs346The ... sample and try again.However, this can be highly inefficient in manycases. For example, if m constraints appear in theordering relation d and the sample is rejected, theN −m random numbers for...
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Báo cáo khoa học: Development of an HSV-tk transgenic mouse model for study of liver damage pptx
... mgÆkg)1) with all possi-ble measures taken to ensure minimum pain and discomfort.Animal experiments were performed according to theNational Institute of Health Guidelines for Care and Use ofLaboratory ... line by mating with male – ⁄ – wild-typeKM mice. Therefore, the F1 and F2 generations of TK5were used for the inducible hepatic injury. In addition,the founder TK3# was also used for preliminary ... lactatedehydrogenase and others. Peripheral blood was extractedfrom the tail vein once a week for 3 weeks for analysis ofALT, AST, total bilirubin and creatinine. Student’s t-test(SAS software) was performed...
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Tài liệu Báo cáo khoa học: Diol dehydratase-reactivating factor is a reactivase – evidence for multiple turnovers and subunit swapping with diol dehydratase pdf
... with 1,2-propanediol as substrate in thepresence of 21 lm AdoCbl and appropriate concentrationsof ATP and MgCl2. In some experiments, ATP and MgCl2were replaced with other nucleotides and ... incubated with the reactivase in the presence of ADP and Mg2+ and followed by nondenaturing PAGE, the bands of theenzyme and the reactivase were markedly reducedin density, and two bands of ... c,e, and g). To determine their subunit compositions,bands i–vi were excised and subjected to SDS⁄ PAGEon 6% and 14% gels (Fig. 5B,C), followed by densito-metric analyses. Both band i and band...
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Tài liệu Báo cáo khoa học: An allosteric DNAzyme with dual RNA-cleaving and DNA-cleaving activities doc
... 25.8 and 53.7 °C.When evaluating the optimal design for a DNAzyme with respect to DNA-cleaving and RNA-cleavingactivities, we found that a number of nucleotides withinthe catalytic core and substrate- binding ... DNAzyme with RNA substrate and RNase A. Such regulatorybiocatalyst systems offer several advantages, includingthe ease of RNA substrate and DNAzyme synthesiswithout any chemical modification, and ... system,most RSs exist in a single-stranded state, and a fewRSs can form a DNAÆRNA duplex with the RNA substrate recognition domain of DRc DNAzyme.RNase A cleaved ssRNA and RNase H specificallyACBFig....
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