... important role in activity.In summary, AP1 was found to function as an ani-onic a- AMP, indicating that it is possible to design a- AMPs by the use of an oblique-orientated a- helicaltemplate. It appears ... Segrest JP, Epand RM, Nie SQ, Epand RF,Mishra VK, Venkatachalapathi YV & AnantharamaiahAntimicrobial properties of an anionic a- helical peptide S. R. Dennison et al.3802 FEBS Journal 273 (2006) ... resulting data points were proximal and, along with those of % 50% of the a- AMPs studied,are candidates to form oblique orientated a- helices.Figure 1B shows that, in an a- helical conformation,AP1...