... discovered in BE and EAC, including frequent gain of chromosomes 6p (1 0–3 7%), 7q (1 7–3 7%), 7p (3 0–6 0%), 8q (5 0–8 0%), 10q (2 0–5 0%), 15q (1 0– 40%), 17q (3 0–5 0%), and 20q (5 0–8 0%); and frequent ... to invasive cancer reflect the cell defense effort in maintaining intracellular homeostasis. Interestingly, a minor down-regulation of PRX2 isoform was detected in ESCC [23,24] suggesting ... Esophageal Cancer – Cell and Molecular Biology, Biomarkers, Nutrition and Treatment 10(Toshimitsu et al., 2004). Aurora-A kinase, a serine/threonine protein kinase, is a potential oncogene....