Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt
... distin-
guish aggregates formed in the presence of Cu
2+
from
those formed in the presence of Zn
2+
.
Taken together, these results suggest that Ab aggre-
gates formed in the presence of Cu
2+
or Zn
2+
are ... the form of aggregates formed in the presence of Cu
2+
[(i) and (iii)] or Zn
2+
[(ii) and (iv)], or as fibrils formed in the...
... stream from the 5¢-terminus of the predic-
ted ORF, is the proper initial codon for a2. The N-ter-
minal amino-acid sequences of the b2 and c2 subunits
corresponded to the sequences of the predicted
PH1751 ... down-
stream from the 5¢-terminus of the predicted ORF, is the
proper initial codon for the a1 gene. The N-terminal
amino-acid sequence of the b1 sub...
... in mutant mtDNA harboring the com-
mon deletion. By applying the specific probe, we can
even detect the presence of the common deletion in the
inner ear in the control group. The proportions of ... 5.1-fold,
respectively.
Increased protein level of TFAM induced by
D-Gal
To further understand the expression of TFAM protein
in the inner ear, western blot analy...
... used in the
synthesis to insure that we would synthesize a tx5a analog
corresponding to the native peptide (irrespective of which
6-bromotryptophan isomer was incorporated in the native
tx5a peptide) ... used. The peptide synthesizer used
conductance monitoring to check the efficiency of the
coupling reactions. In order to scale up t he automated
synthesis to the s...
... inhibit
growth of the strain even in the presence of IPTG
induction. All of these results suggest that the low gene
expression associated with NGG codons in the down-
stream region following the initiation ... paus-
ing at early NGG codons is the reason for the
observed low gene expression.
The length of the peptidyl moiety of the peptidyl-
tRNA in uences...
... activities, the cross-linking
of proteins via N
e
-(c-glutamyl)lysine bonds, the incorpor-
ation of polyamines into proteins, the deamidation of
protein-bound glutamines, and the covalent attachment of
proteins ... allows the organism to develop
substrate and aerial mycelia culminating in the formation of
spores [1]. In contrast, culture in shaking flasks containing...
... to
assess the validity of this dataset. Firstly, the B-factors
of the donor and the acceptor atoms involved in for-
mation of SHBs are compared with those of the atoms
forming normal hydrogen ... are the acceptors com-
monly found for these Tyr side chain donors. The ana-
lysis on pairing frequencies of donor–acceptors has
shown that more than 50% of the accept...
... of pantoate bound in the ATP-binding pocket. Pantoate
binding to the ATP-binding site induced large changes in structure, mainly
for backbone and side chain atoms of residues in the ATP binding
HXGH(34–37) ... [8,9]. One of the
interesting features of the plant PSs is the presence of
a conserved 24 residue insertion in the sequence [9].
This sequence of ami...
... effect of 20E [32]. In
the present study, BIGFLP stimulated BrdU incorpo-
ration into the wing disk in the absence of 20E. How-
ever, the observed synergistic effect of bombyxin
and 20E in other insects ... (1997)
Bombyxin, an insulin-related peptide of insects,
reduces the major storage carbohydrates in the
silkworm Bombyx mori. Comp Biochem Physiol 118B,
349–35...
... nhiệm vụ của công tác trắc địa là đảm bảo khi thi công đào hầm phải đúng theo thiết kế cả về mặt
bằng và độ cao. Bài báo này trình bày phương pháp kiểm tra, từ đó đưa ra nhận xét về khả năng ... tử có độ chính xác cao là phương pháp tối
ưu và có độ chính xác tin cậy, đáp ứng được các đòi hỏi về tiến độ xây dựng, về kinh tế có chi phí thấp và đặc
biệt phương pháp này phù hợp khi thi ......