... terms,and the value of a particular therapy can be properlyevaluated only when compared to another group with similar clinical and histologic characterizations and in the setting of a randomized ... initiated. This part ofthe management cannot be overemphasized. The risks oftreatment with many of the agents are significant and mayhave a substantial latent period (e.g., cyclophosphamide). A ... USAVivekanand Jha, MD, DM, FRCP, FAMS Ste´phan Troyanov, MDPostgraduate Institute of Medical Education University of MontrealChandigarh, India Montreal, CanadaPhilip Kam-Tao Li, MD, FRCP, FACP Jack...