Báo cáo khoa học: Macromolecular NMR spectroscopy for the non-spectroscopist pot

... information can be obtained fromsimple NMR experiments. We then review the use of NMR spectroscopy for determining the 3D structures of macromolecules and examine how tojudge the quality of NMR- derived ... scalewith the size of the NMR magnet.One of the key features that differentiates NMR from most other forms of spectroscopy is that the excited states are relatively long lived, with lifetimes in the ... PR (2011) Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination. FEBS J 278, 704–715.2 Keeler J (2005) Understanding NMR Spectroscopy. Wiley.3...

Báo cáo khoa học: Macromolecular NMR spectroscopy for the non-spectroscopist: beyond macromolecular solution structure determination potx

... al. Macromolecular NMR for the non-spectroscopist IIFEBS Journal 278 (2011) 704–715 ª 2011 The Authors Journal compilation ª 2011 FEBS 715REVIEW ARTICLE Macromolecular NMR spectroscopy for the non-spectroscopist: ... folded and thereforeshould not be used for any subsequent functional experiments.M. Bieri et al. Macromolecular NMR for the non-spectroscopist IIFEBS Journal 278 (2011) 704–715 ª 2011 The Authors ... and the blue spectrum shows the pro-tein saturated with ligand. For each of the resonances indicated with arrows, two peaks are observed at 0.5 : 1, one for the free protein andanother for the...

Báo cáo khoa học: H NMR study of the molecular structure and magnetic properties of the active site for the cyanomet complex of O2-avid hemoglobin from the trematode Paramphistomum epiclitum pdf

... to the iron and positioned toprovide the H-bond to the bound cyanide, and byimplication, to the bound O2in the reduced form in eachof the three globins. The extensive sequence homology for ... 2D NMR experiments [32] that will confirmwhether the active site structure is closer to one or the othercrystal forms, or distinct from both. The hyperfine shifts of the heme are sensitive to the ... from the heme normal (z¢ axis),a is the angle between the projection of the tilt of the z axis on the x¢,y¢ plane (defined direction of tilt of z and the x¢ axis), and j % a + c defines the location...

Tài liệu Báo cáo khoa học: Pathways and products for the metabolism of vitamin D3 by cytochrome P450scc docx

... responsible for the content or functionality of any supplementarymaterials supplied by the authors. Any queries (otherthan missing material) should be directed to the corre-sponding author for the ... determining the substrates from which they arose by the action ofP450scc, as well as the products that they gave rise to.This revealed both the major and minor pathways for the metabolism of vitamin D3 ... spectrum(Fig. 6B), all the expected correlations from 3-CH in the A-ring are the same as in the parent vitamin D3. Thisfurther conﬁrms that no hydroxylation occurs in the A-ring. The new hydroxylated...

Tài liệu Báo cáo khoa học: "A COMPUTATIONAL MECHANISM FOR PRONOMINAL REFERENCE" pot

... antecedence information for personal pronouns contributes to this goal. In the next section, we show how our algorithm overcomes these limitations. 3. THE ALGORITHM Before giving the details of the ... remains. The WML translation for (23) is: (AWARD (THE COMMITTEE) (THE PRIZES) iT001) where IT001 is a WML constant marked for disjoint reference: IT001 ~ (THE COMMITTEES) (THE PRIZES) This information ... dominates the pronoun and searches to the left of the pronoun for any NP nodes that are dominated by an intervening $ or NP node to propose as antecedents. The algorithm then proceeds up to the...

Tài liệu Báo cáo khoa học: "Incorporating Context Information for the Extraction of Terms" pdf

... 1996), incorporating information gained from the textual context of the candidate term. 2 Context information for terms The idea of incorporating context information for term extraction came ... word units in that they cannot be freely modified" (Sager, 1978). Therefore, information from the modifiers of the candidate strings could be used in the pro- cedure of their evaluation ... presents the higher density on terms among any other part of the list. This top of the list, or else, the 'first' of these ranked candidate terms will give the weights to the context....

Báo cáo khoa học: YidC is required for the assembly of the MscL homopentameric pore potx

... impact on the level of the MscL–HA complex, suggesting that the Sec tran-slocon is dispensable for the oligomerization of the MscL subunits.DiscussionWe have analysed the requirements for targeting,membrane ... distance to the plane of the lipid bilayer. In contrast, position 68, which wasused in the earlier study [13], is located adjacent to the centre of the pore-forming TM1. It is thereforeconceivable ... is critical for assembly of the ATP synthase subunits rather than their individualinsertion into the membrane [26].If neither YidC nor the Sec machinery is absolutelyrequired for membrane...

Báo cáo khoa học: " An Input Device for the Harvard Automatic Dictionary" pot

... columns. For example, 0010011 is defined as a token for the Cyrillic letter Й. The symbols circled in the "Lower Case" column are the normal correspondents of the tokens. For example, ... defined as a token for Й in the ranked code, it is nor- mally a token for the semi-colon. Therefore, since the output equipment has not been modified, Cyrillic material in the ranked code still ... to the Univac I. The modified device is performing satisfactorily in the compilation and experimental operation of the Harvard Automatic Dictionary. THE PROPERTIES of a given automatic information-processing...

Báo cáo khoa học: "SMS based Interface for FAQ Retrieval" pot

... t from the dictionary and returns Qt, the set of all ques-tions in the corpus that contain the term t. Wecall the above process as querying the index on the term t. The details of the index ... specify the ∼ symbol at the end of each to-ken of the SMS query. For example, the SMSquery “romg actvt” on the FAQ corpus is refor-mulated as “romg∼ 0.3 actvt∼ 0.3”. The param-eter after the ... exit.foreverEndFigure 2: Pruning Algorithmrithm that efﬁciently ﬁnds the best matching ques-tion for the given SMS query without the need togo through all the questions in the FAQ corpus.The...

Báo cáo khoa học: "A Common Framework for Syntactic Annotation" pot

... variouslevels. The process allows one to specify, on the one hand, the informational properties of the scheme (i.e., its capacity to represent a givenpiece of information), and, on the other, the way the ... eliminating the need for the intermediary concrete AML format. However,especially for existing formats, it is typically morestraightforward to perform the two-step process.• type : specifies the node ... labels for constituents. Somegrammatical roles (subject, object, etc.) areimplicit in the structure of the encoding: for instance, the nesting of the NP the front roomimplies that the NP is the...

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