... to the TNFR1 trimers in the plasma mem-brane early after receptor ligation whereas the cell death regulators FAS-associated via death domain(FADD) and caspase 8 are recruited to a pro-apopto-tic ... cellular inhibitor of apoptosis protein; FADD, FAS-associated via death domain;IjBa, inhibitor of kappaB alpha; IKK, IjB kinase; NEMO, NF-jB essential modulator; NF-jB, nuclear factor kappaB; RIP1, ... NEMO adaptorbridges the nuclear factor-kappaB and interferonregulatory factor signaling pathways. Nat Immunol 8,592–600.73 Ashida H, Kim M, Schmidt-Supprian M, Ma A, Ogawa M & Sasakawa C...