... (Promega Corp Madison, WI), or using an MTT [3- (4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide] assay.[24] Statistical analysis Statistical analyses were performed using Sig-maStat ... Acad Sci USA 2006; 1 03( 39): 14584-14589. 16. Yamaguchi H, Sasaki K, Satomi Y, Shimbara T, Kageyama H, Mondal MS, Toshinai K, Date Y, Gonzalez LJ, Shioda S, Takao T, Nakazato M, Minamino N. Peptidomic ... could negatively influence clinical disease in ALS. Thus our study for the first time tenta-tively supports the hypothesis that a mechanism thorough which abnormal metabolism may ultimately influence...