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Novel technique for rapid detection of a-globin gene mutations and deletions pot

Novel technique for rapid detection of a-globin gene mutations and deletions pot

Novel technique for rapid detection of a-globin gene mutations and deletions pot

... Novel technique for rapid detection of a-globin gene mutations and deletions JINGZHONG LIU, XINGYUAN JIA, NING TANG, XU ZHANG, XIAOYI ... frequencies of a-thalassemia caused by a-globin gene mutations and deletions. This studywas designed to find an efficient and simple diag-nostic test for the mutations and deletions. Translational SignificanceA ... for carrier couples and for prenatal diagnosis of conceptionby couples who are both carriers of this type of gene de-letion. Diagnostic assays of the a-thalassemia-2 are alsoimportant for genetic counseling,...
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 Báo cáo y học:

Báo cáo y học: "Comparison of a Two-Lead, Computerized, Resting ECG Signal Analysis Device, the MultiFunction-CardioGramsm or MCG (a.k.a. 3DMP), to Quantitative Coronary Angiography for the Detection of Relevant Coronary Artery Stenosis (70%)

... al. Systematic review of the effectiveness and cost-effectiveness, and economic evaluation, of myocardial perfusion scintigraphy for the diagnosis and management of angina and myocardial infarction. ... USA alone the prevalence of CAD is estimated at 5.9% of all Cauca-sians of age 18 and older [3]. Accurate, non-invasive diagnosis of, and screening for, CAD and restenosis after coronary ... sensitivity, speci-ficity, and negative predictive value of 97%, 79%, and 98% respectively, for females 65 years of age or older is superior to published data for stress ECG and stress perfusion...
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Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens

Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens

... YG3003 and/ or YG7108 strain, and 21 chemicals (8.2%) formed 8-OH-Gua in the rat hepatocytes oxidized DNA.These results may demonstrate the utility and limitation of both the Ames test and 8-OH-Gua ... 8-OH-GuaIntroductionGenotoxicity of carcinogens is considered one of the most important contributors to cancer and a marker of the cancer risk of various populations. There are a number of short-term genotoxicity ... 4-nitroquinoline-1-oxide and asbestos causes formation of 8-OH-Gua in their respective targetorgans (Floyd 1990). Herein we report the genotoxicity of 255 chemicals performed by two kinds of experiments;...
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Critical evaluation of diagnostic aids for the detection of oral cancer docx

Critical evaluation of diagnostic aids for the detection of oral cancer docx

... document potential areas of loss of autofluorescence that might be indicative of cyto-logic and/ or molecular changes indicative of premalignan-cy. Nineteen of 20 tumors demonstrated loss of autofluorescence ... shownto have sensitivity and specificity rates of 93 and 98%.15,16One explanation for this discrepancy is that early lesions of oral cancer and precancer are often subtle and rarelydemonstrate ... standard of histopathologic analysis,appropriateness of patient population, use of proper studyclinicians, specificity and potential for replication are satis-fied. Improving oral cancer detection...
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INTERNATIONAL STANDARD Microbiology of food and animal feeding stuffs — Horizontal method for the detection of Salmonella spp docx

INTERNATIONAL STANDARD Microbiology of food and animal feeding stuffs — Horizontal method for the detection of Salmonella spp docx

... °C and leave for several minutes (approximately 5 min). Add 0,25 ml of the reagent for detection of β-galactosidase and mix. Replace the tube in the water bath set at 37 °C and leave for ... portion and initial suspension 9.1.1 General See ISO 6887-1 and the specific International Standard dealing with the product concerned. See ISO 8261 for milk and milk products. For preparation of ... contents of MgCl2⋅6H2O from a newly opened container, according to the formula. For instance, 250 g of MgCl2⋅6H2O is added to 625 ml of water, giving a solution of total volume of 788 ml and...
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ag doped wo3-based powder sensor for the detection of no gas in air

ag doped wo3-based powder sensor for the detection of no gas in air

... values (TLV) for NO2 and NOare 3 and 25 ppm, respectively [5]. Therefore, a NOxsensorrequires high sensitivity for detecting low concentration of gases. Another enormous driving force for developing ... to monitorthe concentration of NO and NO2gases because of the lowconcentration, one of the roles of the Ag is apparent toprovide surface for the conversion of NO to NO2accordingto the ... beam of nickel ®ltered Cu Karadiation (l  0:154 nm). This was obtained from a curvedFig. 4. XRD spectra of WO3before and after the NO exposure.Fig. 5. XRD spectra of 1% Ag/WO3before and...
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Serum Biomarkers for Early Detection of Gynecologic Cancers ppt

Serum Biomarkers for Early Detection of Gynecologic Cancers ppt

... SELDI-TOF-MS to identify candidate markers for endometrial cancer [62]. Two of the candidates turned out to be apolipoprotein A-1 and apolipoprotein C-1. Dual-biomarker analysis for the detection ... resulting from the lack of reliable, sensitive screening tests and our limited understanding of the mechanisms of chemoresistance and relapse. More than two-thirds of cases of ovarian cancers are ... pre-treatment-elevation of serum IAP in 53% of squamous cell carcinoma cases, and in 40% of adenocarcinoma patients [34]. IAP level is related to disease stage and lymph node metastasis, and is of predictive...
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Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx

Báo cáo khoa học: A novel pathway for sequential transformation of 7-dehydrocholesterol and expression of the P450scc system in mammalian skin pptx

... the Center of Excellence inConnective Tissue (to A.S. and J.Z.) and Center of Excellence inGenomics and Bioinformatics (to A.S.), UTHSC, and NIH grants1R01-AR047079-0 1A2 (to A.S.) and RR017854. ... thank ProfessorCedric Shackelton, Children’s Hospital Oakland Research Institute,Oakland, CA, USA for performing G C/MS an alyses, and Pr ofessorWalter Miller, U niversity o f C alifornia, ... Belarus;6Children’s HospitalOakland Research Institute, Oakland, CA, USA;7Department of Biochemistry and Molecular Biology, School of Biomedical and Chemical Science, University of Western Australia,...
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Báo cáo khoa học:

Báo cáo khoa học: "A Figure of Merit Technique for the Resolution of Non-Grammatical Ambiguity" ppt

... BUILDING(s) (of) ONE/ALONE (of) DOUBLE/GEMINATE (of) ANNUAL/YEARS (of) LAYER/LAMELLA (of) (to /for) (by/with/as)LINE (of) THIN-CRUST(s) HOW/AS/BUT (of) (to /for) (by/with/as)FOSSILIZED (of) (to /for) - ... sults of applying the technique to a set of twenty one Russian sentences indicate that the technique can be successful in about 90% of the cases. The technique can easily be adapted for use ... University of Washington, Linguistic and Engineering Studies in Automatic Translation of Scientific Russian into English, Department of Far Eastern and Slavic Languages and Department of Electrical...
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a novel method for the synthesis of titania nanotubes using

a novel method for the synthesis of titania nanotubes using

... nanotubes. On theother hand, the formation of the nanotubes using conventionalmagnetic stirring is retarded by the formation of a double layer and diffusion-limited transport of the species. A better ... pit formation continuing until repassivation oc-curs [17,19]. Nanotube formation goes through the diffusion of F−ions and simultaneous effusion of the [TiF6]2−ions.The faster rate of formation ... photo-catalytic activities and has great potential in many areas, includ-ing environmental purification, gas sensors, photovoltaics, im-mobilization of biomolecules, and generation of hydrogen gas[1–12]....
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