**Báo cáo khoa học: Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth* potx**

Báo cáo khoa học: Functionally distinct dopamine and octopamine transporters in the CNS of the cabbage looper moth* potx

... insect; neurotransmitter; transporter; dopamine; octopamine; cocaine. The catecholamine dopamine (DA), the phenolamine octopamine (OA) and the indolamine serotonin (5-HT) in uence a variety of ... does the moth OAT substitute for DAT in dopami-nergic signaling pathways in the moth CNS, and what is the nature of the mechanism that substitutes for OAT in the octopaminergic pathways in the ... mostclosely with transporters of epinephrine and norepineph-rine, compounds that are little used in the invertebratenervous system. The occurrence of an OAT in the cabbage looper suggests DATs...

Báo cáo khoa học: Increased glucose metabolism and ATP level in brain tissue of Huntington’s disease transgenic mice pdf

... nature of the involvement of GAPDH and the CAG expansion of the mutant huntingtin protein.One such scenario is that the interaction between poly-glutamine-containing proteins and GAPDH results in a ... bobbing, head tilting and circling. The levels of the endogenous (wild-type) huntingtinprotein and the transgene product were examined bywestern blotting using anti-huntingtin serum raisedagainst ... were the sole initial change in HD. The mathematical modellingbased upon the measured kinetic parameters of the individual enzymes determined experimentally(Table 2) and the rate equations of the...

Tài liệu Báo cáo khoa học: "Detecting Semantic Equivalence and Information Disparity in Cross-lingual Documents" doc

... correlation between the proportion of matching terms and the correct entail-ment decisions is less strong. In such framework, forinstance, the full mapping of the hypothesis into the text is per ... matching targets the increase of CLTE precision. Adding syntactic con-straints to the matching process, DR features aim toreduce the amount of wrong matches often occur-ring with bag -of- words ... representations of T and H, for each grammati-cal relation (r) we calculate a DR matching score as the number of matching occurrences of r in T and H, divided by the number of occurrences of r in H.Separate...

Tài liệu Báo cáo khoa học: "Paraphrasing Using Given and New Information in a Question-Answer System" docx

... reflecting the division of given and new information In the question. The design of the tree allows for a simple set of rules which flatten the tree. The final stage of processing in the paraphraser ... of the tree. 1"Ne subject of the main verb is the root node of the left subtree, the object (if there is one) the root node of the right subtree. In the current system, the use of binary ... both the problem of ambiguity and the rephrasing of the question. It makes the system's interpretation of the question explicit by breaking down the clauses of the question and reordering...

Báo cáo khoa học: D-strand perturbation and amyloid propensity in beta-2 microglobulin ppt

... intermolecularcross-b interactions in the native protein. On the otherhand, the location of His5 1in the D-strand is intrigu-ing: in native b2m, the His51 side chain points out-wards, although, in the structures ... structures where the protein is in a nonmonomeric state. Because the inser-tion of a proline breaks the regularity of a b-strand asa result of restrictions of the / and w angles, the resulting (partial) ... on the role of residue 53 isavailable: Asp53 is predicted to map at the center of along b-strand [20] and to be involved in intermolecularinteractions [19]. On the other hand, the side chain...

Báo cáo khoa học: Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide attenuate the cigarette smoke extract-induced apoptotic death of rat alveolar L2 cells ppt

... and PACAP exert their neuronal actions in the central and peripheral nervous systems via the stimulation of variousprotein kinases, including the phospholipase C/proteinkinase C (PKC) and the ... identified and charac-terized with a radioligand-binding assay using125I-labelledVIP, and the binding affinities of VIP and PACAP27 forthese receptors were examined. Rosenthal analysis of the specific ... 2004Effect of VIP on the CSE-induced activation of caspase-3 The biochemical features of apoptosis include the activa-tion of one or more cysteine proteases of the caspasefamily. To examine the possible...

Báo cáo khoa học: Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation doc

... consisting of up to four partially overlappingsteps [42], namely (a) the insertion of Pex11 into the membrane, (b) the elongation of peroxisomes, (c) the segregation of Pex11 and the formation of ... domain (GED), which activatesGTPase activity and mediates self-assembly, and aproline and arginine-rich domain (PRD) that mediatesinteractions with SH3 domains of effector proteins of the actin ... of PPPs and DRPs?Interestingly, a double deletion of PEX28 and PEX29can be complemented by the overexpression of Vps1or Pex25, indicating a genetic interaction of members of the two protein...

Báo cáo khoa học: "Balancing User Effort and Translation Error in Interactive Machine Translation Via Conﬁdence Measures" pot

... accuracy (Gandrabur and Foster, 2003; Ueff-ing and Ney, 2005). In this work, we propose a fo-cus shift in which CMs are used to modify the in- teraction between the user and the system instead of modify ... translation she has in mind and the total number of words in the sentence. In thiscontext, a word-stroke is interpreted as a single ac-tion, in which the user types a complete word, and is assumed ... Here, wewill focus on the Spanish–English part of the EUcorpora. The corpus is divided into training, de-velopment and test sets. The main ﬁgures of the corpus can be seen in Table 1.As a ﬁrst...

Báo cáo khoa học: "Disambiguating Between Generic and Referential “You” in Dialog ∗" ppt

... labelers an-notated the training and test sets; none of the au-thors were involved in labeling the test set. Table 1presents information about the number of instances of each of these classes found.4 ... conversations, yielding 85 utterances con-taining “you”; the task was reported to be easy, and the kappa was 100%.We then annotated a total of 42 conversations fortraining and 13 for testing. Different ... Switchboard (Godfrey et al., 1992).tecting the fact that a task is being assigned, and in identifying the owner. While there is an increas-ing body of work concerning addressee identiﬁca-tion (Katzenmaier...

Báo cáo khoa học: UDP-galactose 4-epimerase from Kluyveromyces fragilis – catalytic sites of the homodimeric enzyme are functional and regulated docx

... revived interest in exploring the regulatory behavior of this enzyme. Toavoid misinterpretation of the results, the composition and stoichiometry of the bound cofactor(s) and the stability of the ... been used in the context of binding of the inhibitor 5¢-UMP to epimerase. The terms native, inhibitor-free and monomeric epimerasehave been used in the context of kinetic properties of the enzyme.Reagentsd(+)-Gal, ... presence of 0.15 mm 5¢-UMP, which corresponded closely to the transition midpoint of abolition of the kinetic lag. In the case of inactivation by trypsin, the proﬁle distinctlyindicated the existence...

Xem thêm