... Structure and positioning comparison of two variants of penetratin
in two different membrane mimicking systems by NMR
Mattias Lindberg, Henrik Biversta
˚
hl, Astrid Gra¨ slund and Lena ... importance of the positioning
in the membrane. When changing the two tryptophans
(residue 48 and 56) of penetratin to phenylalanines it was
shown that the...
... hypermethy-
lated and maintained in a repressed state by MBD
proteins [202]. As summarized in Fig. 6, repressed CG
islands are likely to be maintained in an inactive state
by a variety of cooperating repressive ... modulation of chromatin
structure and transcription by nucleosome binding
properties of PARP-1. Cell 119, 803–814.
111 Ryoji M & Worcel A (1985) Struct...
... and C-terminal domain in red. (B) Ribbon representation of the structure of the PSI domain of barley prophytepsin [25] (N-terminal domain,
blue; C-terminal domain, red). (C) Model structure of ... followed by a prosegment of about 40 amino
acids, and a N-terminal domain and a C-terminal domain
separated by an insertion comprising approximately 100
amino acids, named...
... the N-terminal FP, it would
be of interest to compare the structure of the internal FP
and i ts interaction w ith membrane bilayer, including in
particular the structural in uence of proline. Consistent
with ... Veeramuthu,
B.,Kantchev,A.B.,Wu,W.G.&Chang,D.K.(2003)Effectsof
alterations of the amino-terminal gly cine of in uenza hema-
gglutinin fusion peptide on its str...
... b2-strand), where it con-
tacts both the invariant GXXG motif and the variable
loop.
Nucleic acid binding by tandem but independent
KH domains – NMR structure of the KH3 and KH4
domains of FBP in ... arrangement of mole-
cules produces two protein–protein interfaces. (B) One protein–protein interface generated by two- fold NCS. (C) Other protein–protein inter-
faces als...
... six-stranded parallel b-sheet flanked by a varying
number of a-helices. Residues involved in binding of
the cofactor ThDP are located at the C-terminal ends
of the b-strands of Dom-c (diphosphates and ... Mg
2+
)
and of Dom-a¢ of a neighbouring subunit (pyrimidine
moiety). The active centre is defined by the thiazolium
ring of ThDP, which sits in a deep pocket opening...
... ATP-binding
subdomains, indicating a common structure of the ATP-
binding sites of the two enzymes. Interestingly, five of the six
cysteines of GlcNAc kinase had an equivalent cysteine
in glucokinase, not always in ... align-
ments of glucokinase and GlcNAc kinase and the common
ATP-binding domain, the GlcNAc kinase was fitted into the
glucokinase model using RasMol softwa...
... LF:Information
Structure
I
I
Structure
~Phonological Form(
Figure 1: Architecture of Standard Metrical
Phonology
The involvement of two apparently uncoupled lev-
els of structure in ... related to distinctions of discourse focus
among the concepts and open propositions that the
speaker has in mind.
The proof of this claim lies in showing that the
rules of...
... DMT1-TM4 in TFE and SDS.
Ó FEBS 2004 Structure and topology of TM4 of DMT1 (Eur. J. Biochem. 271) 1951
Structure and topology of the transmembrane domain 4 of the
divalent metal transporter in membrane- mimetic ... of DMT1 since the
discovery of this gene, there has so far been no structural
characterization of either this integral protein or a segment
of it. An...
... to
the H
a
and side chain protons. The spin systems of Lys10 and Arg11 are indicated by rectangles as both contain a second H
N
in the side chain. The
N-terminal Gly1 appears as a weak and very ... for small proteins [13] using the
computer program
NDEE
(Spin Up, Lu
¨
nen, Germany).
Owing to the high abundance of the amino acids valine,
leucine and isoleucine in the sequen...