Báo cáo khoa học: On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes ppt

... linkage on the severe restriction of the space availablefor the passage of nascent proteins through the tunnel by the swung conformation of L22; on the conservation of the L22 double-hook; and on the ... 270) Ó FEBS 2003 THE EMBO LECTURE On peptide bond formation, translocation, nascent protein progression and the regulatory properties of ribosomes Delivered on 20 October 2002 at the 28th FEBS Meeting ... spiral rotation of  180° of the 3¢ end of the A-site tRNA, performed in conjunction with peptide bond formation, and the shift of the acceptor stems of the tRNA. Sovereign motions of structural...

Tài liệu Báo cáo khoa học: What makes biochemical networks tick? A graphical tool for the identiﬁcation of oscillophores ppt

... second combined autoinﬂuence path consists of onecycle going through the two species and two reactions on the l eft hand side of t he subgraph, and one n egative halfstep on the right hand ... equationtherewith corresponds to a sum of minus paths in the network, is the basis of the graphical analyses of the characteristic equation and of t he method we develop here.Inspection of Eqn ... Not only the control of ﬂux but also the control of the occurrence o f oscillations is asubtle function of network topology and (in the morecoarse-grained approaches) enzyme elasticitie s. There...

Báo cáo khoa học: IMP1 interacts with poly(A)-binding protein (PABP) and the autoregulatory translational control element of PABP-mRNA through the KH III-IV domain pdf

... have further characterized the interaction between PABP and IMP1 on the ARSRNA for a better understanding of their role in trans-lational regulation of PABP expression. The results of our studies ... investigation is whether dimerizationbetween PABP and IMP1 prior to binding the RNAcould alter their binding site on the ARS.To understand the molecular nature of the interac-tion of IMP1 with the ... synthesize the PABP peptides.PABP and IMP1 binding region of the ARSWe have shown earlier that at least three polypeptidesPABP, IMP1, and UNR bind to the ARS element of PABP mRNA, and among these...

Tài liệu Báo cáo khoa học: A peptide containing a novel FPGN CD40-binding sequence enhances adenoviral infection of murine and human dendritic cells doc

... [the ﬁnal peptide concentrationused ranged from 0 (controls) to 15 lM, and adenovirus wasadded at a concentration consistent with the ﬁnal desiredmultiplicity of infection (m.o.i.) for the ... upon the expression of CD40 on the cell surfaceto enhance adenovirus infectivity.FPGN2-KBP enhancement of adenovirus infection of DCrequires the FPGN motif and is dose-dependentTo explore the ... infection. The number of GFP-positive cells was consistently higherwith immature DC than with mature DC, regardless of whether or not AdV-GFP infection was enhanced by the addition of peptide. At the...

Tài liệu Báo cáo khoa học: "A Method for Correcting Errors in Speech Recognition Using the Statistical Features of Character Co-occurrence" pptx

... candidates, when one of their Error-Parts includes the other, and their frequencies are the same value, the candidate whose Error-Part includes the other is accepted. Condition of Inclusion-2: ... applying a portion of a regular expression to an erroneous section. Instead of this portion of the regular expression, SSC uses a collection of strings, the members of which are in the corpus ... ~-"~', etc. These results confirm that our method is effective in improving the understanding of the recognition results. On the other hand, there were four level-down cases. Three of these cases...

Báo cáo khoa học: "Who, What, When, Where, Why? Comparing Multiple Approaches to the Cross-Lingual 5W Task" pptx

... for the monolingual 5W task and not modified to handle MT. They used hand-crafted rules on the output of the latent annotation parser to extract the 5Ws. English-function used the function ... from the parser to map parser constituents to the 5Ws. First the Who, When, Where and Why were ex-tracted, and then the remaining pieces of the sen-tence were returned as the What. The goal ... models and lexical trigger models. Of the nine systems, six were phrased-based systems (one of these used chunk-level reordering of the Chinese, one used word sense disambiguation, and one used...

Báo cáo khoa học: "Parsing with Treebank Grammars: Empirical Bounds, Theoretical Models, and the Structure of the Penn Treebank" ppt

... representation and tree transformations,but little by top-down vs. bottom-up strate-gies. We discuss grammatical saturation, in-cluding analysis of the strongly connectedcomponents of the phrasal nonterminals ... grammar. The resulting analysis builds on the presentation of Charniak (1996), but extendsit by elucidating the structure of non-terminal inter-relationships in the Penn Treebank grammar. On the basis ... NN:[2,3])3.1 Time The parser has an theoretical time bound,where is the number of words in the sentence to beparsed, is the number of nonterminal categories in the grammar and is the number of (active)...

Báo cáo khoa học: "Using Leading Text for News Summaries: Evaluation Results and Implications for Commercial Summarization Applications" ppt

... portion of the BODY field and labels it the "LEAD" field. The amount of the BODY field that is in- eluded in the LEAD is based on document length. Minimum thresholds for the number of ... as products and their prices, or companies and corre- sponding stock quotes. In rare instances, the BODY of a list type document includes a brief description of the contents of the list that ... stories, based on past in- formal observations of LEAD fields. Because of the query bias, the test corpus does not represent our news database. For example, only 5.5% of the documents in the test...

Báo cáo khoa học: Heavy metal ions inhibit molybdoenzyme activity by binding to the dithiolene moiety of molybdopterin in Escherichia coli pdf

... the insertion of metalions into MPT beyond the reaction by the MogA and MoeA proteins. The insertion of copper, cadmium and arsenite is independent of the MogA and MoeA pro-teins. Even if the ... addition of these metals at concentrations of up to1mm to the reaction mixture did not result in theirinsertion into MPT (data not shown). In addition, wetested the insertion of metal ions into ... for the insertion of nonspe-ciﬁc metal ions. Only in the presence of high molyb-date concentration is MPT released and molybdateinserted. This result may imply that, under conditions of high...

Báo cáo khoa học: Hodgkin Reed–Sternberg cells express 15-lipoxygenase-1 and are putative producers of eoxins in vivo Novel insight into the inﬂammatory features of classical Hodgkin lymphoma ppt

... expression of 15-LO-1 but not of 15-LO-2 in L1236 cells (data notshown). To demonstrate the expression of the 15-LO-1 protein in L1236 cells and the cellular localization of the enzyme in the presence ... (Fig. 8B). The levels of these metabolitesincreased with the concentration of arachidonic acid and a plateau was reached at a concentration of 40 lmarachidonic acid.Expression of 15-LO-1 in ... witharachidonic acid. (A) The concentration of arachidonic acid was40 lM. (B) Five minutes of incubation with the indicated concentra-tion of arachidonic acid. One typical experiment out of three isshown....

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