Báo cáo khoa học: "Computational Modeling of Human Language Acquisition" ppt
Tài liệu Báo cáo khoa học: Autolytic activity of human calpain 7 is enhanced by ESCRT-III-related protein IST1 through MIT–MIM interaction pptx
... the C-terminal half of PacC [16]. A human ortholog of PalA, ALIX (also known as AIP1), functions in thebudding of enveloped RNA viruses from plasmaY. Osako et al. Enhancement of calpain 7 autolysis ... localization of calpain 7. As shownin Fig. 9A, overexpression of FLAG–IST1 did notenhance the autolysis of mGFP–calpain 7 in culturedcells. On the other hand, overexpression of FLAG–IST1DMIM1,2suppressed ... mechanisms of calpain 7 in vitro:(a) by binding of MIM, MIT domains dissociate fromthe protease domain to expose the catalytic core; and(b) binding of MIM causes a conformational change of calpain...
- 15
- 505
- 0
Tài liệu Báo cáo khoa học: Reversible tetramerization of human TK1 to the high catalytic efficient form is induced by pyrophosphate, in addition to tripolyphosphates, or high enzyme concentration ppt
... Structures of thymidine kinase 1 of human andmycoplasmic origin. Proc Natl Acad Sci USA 101,17970–17975.15 Sabini E, Ort S, Monnerjahn C, Konrad M & Lavie A(2003) Structure of human dCK ... B(2004) Effect of valine 106 on structure–function rela-tion of cytosolic human thymidine kinase. Kinetic prop-erties and oligomerization pattern of nine substitutionmutants of V106. Eur J ... the part of the phosphatedonor that is necessary for the dimer–tetramer transi-tion of native hTK1 purified from human lymphocyteswas identified. Further, the effect of the concentration of the...
- 10
- 647
- 0
Tài liệu Báo cáo khoa học: Biochemical characterization of human 3-methylglutaconyl-CoA hydratase and its role in leucine metabolism docx
... small amounts of HMG-CoA and large amounts of free CoA. Peak 4 produced HMG-CoA and also large amounts of free CoA. Peak 5 produced large amounts of HMG-CoA, but also free CoA. Human 3-methylglutaconyl-CoA ... The production of (Z)-3-MG-5-CoA by Gct is probably due tothe possible trans-conformation of the5-carboxyl group of (Z)-3-methylglutaconate.Table 2. Kinetic constants of AUH (human 3-methylglutaconyl-CoAhydratase).SubstrateKm(lM)Vmaxa(UÆmg)1)kcat(s)1)kcat⁄ ... bifunctional protein was named AUH (‘AU bind-ing homolog of enoyl-CoA hydratase’). The RNA-binding activity of the human protein and also of themurine homologue was investigated further, its biologi-cal...
- 11
- 625
- 0
Tài liệu Báo cáo khoa học: High activity of human butyrylcholinesterase at low pH in the presence of excess butyrylthiocholine pptx
... themechanism of action of chymotrypsin: the role of the low barrierhydrogen bond. Biochemistry 36, 4576–4584.46. Warshel, A. (1998) Electrostatic origin of the catalytic power of enzymes and the role of ... general features of therecently determined X-ray structure of human BuChE [7,8].In particular, most of the essential features of the catalyticsite (i.e. a catalytic triad of Ser-His-Glu, an ... structure and mechanism of catalysis. Annu. Rev. Biochem. 46, 331–358.43. Blow, D.M., Birktoft, J.J. & Hartley, B.S. (1969) Role of a buriedacid group in the mechanism of action of chymotrypsin....
- 10
- 680
- 0
Tài liệu Báo cáo khoa học: Constitutive oligomerization of human D2 dopamine receptors expressed in Spodoptera frugiperda 9 (Sf9 ) and in HEK293 cells Analysis using co-immunoprecipitation and time-resolved fluorescence resonance energy transfer pdf
... protein-coupled receptors (GPCR) represent one of the largest families of genes in the human genome. They areresponsible for the detection of a large variety of stimuli andcontrol many physiological ... Strange11School of Animal and Microbial Sciences, University of Reading, Reading, UK;2GlaxoSmithKline, New Frontiers Science Park,Harlow, UK Human D2Long(D2L)andD2Short(D2S) dopamine receptorisoforms ... interaction. A combination of several methodsseems therefore important for the demonstration of GPCRoligomerization.The D2dopamine receptor is a member of the D2-likefamily of dopamine receptors...
- 11
- 618
- 0
Báo cáo khoa học: Catalytic digestion of human tumor necrosis factor-a by antibody heavy chain pot
... conformation of ETNF-6mAbSequencing of the cDNA of the variable region of ETNF-6 mAb was performed, and this was followedby molecular modeling of its three-dimensional struc-ture. The heavy chain of ... the Ser5-Arg6 bond of TNF-a at the first step, resulting in the generation of a fragment of 17 kDa. This fragment was digested to a smaller molecule of 15 kDa byscission of the Gln21-Ala22 ... Aftera reaction time of 47.2 h, the amount of TP41-1 at aretention time of 11 min decreased, because of frag-mentation. The fragment was observed at a retentiontime of 13 min (indicated by...
- 10
- 491
- 0
Báo cáo khoa học: Unusual stability of human neuroglobin at low pH – molecular mechanisms and biological significance docx
... H64Q mutant of Ngb was followed by measuring the decrease in intensity of the Soret band (Ngb, kmax of 412 nm; H64Q, kmax of 406 nm; Mb, kmax of 409 nm) in the absorption spectra of the proteins, ... by proton-ation of amino acid side chains. The amino acidsequence of human Ngb, with respect to the acid-labilehorse and human Mbs, displays a high degree of sub-stitution of charged amino ... CRIBI Biotechnology Center, University of Padua, Italy2 Department of Biochemistry, University of Antwerp, Belgium3 Department of Zoophysiology, University of Aarhus, DenmarkIntroductionNeuroglobin...
- 13
- 495
- 0
Báo cáo khoa học: Nuclear localization of human spermine oxidase isoforms – possible implications in drug response and disease etiology pptx
... stableoverexpression of any of the human spermine oxidaseisoforms in human tumor cells. Furthermore, wereport the first direct visualization of the localization of human spermine oxidase in a human tumor ... combination of the human isoforms 1 and 4, had been identified. The dis-covery of its existence in the mouse suggested the like-lihood of a human homologue, and led us to pursuethe identification of human ... ª 2008 FEBSeach of the isoforms of interest to confirm cellularlocalization. In contrast to results observed with thehomologous mouse SMO isoforms, each of the three human isoforms examined...
- 12
- 395
- 0
Báo cáo khóa học: Some properties of human small heat shock protein Hsp20 (HspB6) potx
... summa-tion of the elution profiles of the isolated 3D mutant of Hsp27 andisolated wild-type Hsp20 is presented on curve 1. Experimental elutionprofiles of the mixture of the 3D mutant of Hsp27 ... L of E. coli culture. As in the casewith Hsp20, all stages of Hsp27 purification were performedin the absence of urea or detergents.Oligomeric state of recombinant human Hsp20Recombinant human ... chromatography of recombinant human wild-typeHsp20. (A) Lack of effect of dilution or sample volume on the apparentmolecular mass of Hsp20. Equal volumes (240 lL) containing 624 lg(1) or 72 lg (2) of Hsp20,...
- 12
- 372
- 0
Từ khóa: Nghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngNghiên cứu tổ hợp chất chỉ điểm sinh học vWF, VCAM 1, MCP 1, d dimer trong chẩn đoán và tiên lượng nhồi máu não cấpMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPNghiên cứu vật liệu biến hóa (metamaterials) hấp thụ sóng điện tử ở vùng tần số THzGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu khả năng đo năng lượng điện bằng hệ thu thập dữ liệu 16 kênh DEWE 5000Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtBÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015TÁI CHẾ NHỰA VÀ QUẢN LÝ CHẤT THẢI Ở HOA KỲQUẢN LÝ VÀ TÁI CHẾ NHỰA Ở HOA KỲ