Báo cáo khoa học: Examining multiprotein signaling complexes from all angles The use of complementary techniques to characterize complex formation at the adapter protein, linker for activation of T cells pdf
... also
interact with LAT, but whether these proteins directly or indirectly
associate with LAT is still controversial. The result of the formation
of LAT-mediated complexes is the activation of signaling ... 5435
MINIREVIEW
Examining multiprotein signaling complexes from all
angles
The use of complementary techniques to characterize complex
for...
... enhancer targeting in
the Abd-B domain. The observation that the larger the
deletion within this region, the stronger the resulting
trans regulation, indicates that the critical region is
built up from ... difference in the tim-
ing of somatic pairing perhaps reflects the difference
between the complexities of the regulation of the two
systems: a longer time is...
... the
absence of STARS. The actin mutant that favors
F-actin formation and increases the F-actin ⁄ G-actin
ratio [56] stimulates MRTF activity, even in the
absence of STARS, and abolishes further activation ... G-actin, but does not alter the F-actin ⁄
G-actin ratio, reduced the ability of STARS to activate
MRTF-dependent transcription. Wild-type actin did
not significant...
... in vitro, either
because its concentrations were below the detection
limit or because of the lack of the l-gulono-1,4-lactone
substrate in these cells. l-Gulono-1,4-lactone can be
formed by the ... to determine the enzymatic activity of the
GST-tagged Rv1771 protein of M. tuberculosis, the
oxidase activity was tested in the presence of the l-gul-
ono-1,4-lactone...
... inactive. This led to the assumption that
there is regulation between the catalytic sites. Func-
tionality could be restored after replacement of the
inhibitor by a substrate [14]. Therefore, either ... circumference of the lobe next to the
site indicates susceptibility to the protease; +UMP and –UMP indicate its association and dissociation; the arrow on the top of...
... include identifica-
tion of these lesions as a strand break, verification of
the nature of the 3¢ end, and identification of a satis-
factory pathway for repair. The XRCC1 component of
the XRCC1–DNA ... specific protein that is required to progress the
particular lesion to the next stage of repair. Therefore,
Pol b initiates repair of single-nucleotide gaps, PNK is...
... document collection pairs. The
little the overlap of the range of distribution di-
vergence, the sharper the test of different perspec-
tives.
To account for large variation in the number of
words ... Quality of Monte Carlo Estimates
The Monte Carlo estimates of the KL divergence
from several document collection pair are listed in
Table 2. A complete list of...
... does the moth OAT substitute for DAT in dopami-
nergic signaling pathways in the moth CNS, and what is the
nature of the mechanism that substitutes for OAT in the
octopaminergic pathways in the ... indicating that the K
TrnDAT
m
for
Na
+
must be greater than 100 m
M
,asseeninTrnOAT[12].
The uptake of [
3
H]DA by cells expressing TrnDAT and
TrnOAT was inhibited by...
... differences in activity
of the respective regulatory elements due to interactions
rather than in the use of distinct, tissue-specific regulatory
elements.
Glucocorticoid sensitivity of the regulatory sequences
All ... respect to their regulatory activity. To
test this hypothesis, we examined the combinatorial effects
of modular deletions in the distal upstream and fi...
... during the transfer of
these electrons is used to pump protons from the mito-
chondrial matrix towards the inner membrane space,
thereby creating a proton gradient. The energy stored
in the proton ... accu-
mulation between non-P-glycoprotein-containing cells
and the same cells transfected in such a way that they
express this protein. We demonstrated that in cells that...