... HO-1 and mammalian HO- 1 (in parentheses) are shown. Hydrogen bondingpatterns in the ÔopenÕ and ÔclosedÕ conformations and in the ÔmoreclosedÕ conformation are characterized by a- helix and p-helix,respectively.4520 ... T., Matsuno, A. , M uraki, A. ,Nakazaki, N., Naruo, K., Okumura, S., Shimpo, S., Takeuchi, C.,Wada, T., Watanabe, A. , Yamada,M.,Yasuda,M.&Tabata,S.(1996) Seque nce analysis of the genome of ... Yoshida, Yamaguchi, Japan;3Department of Biochemistry,Yamagata University School of Medicine, Yamagata, JapanHeme oxygenase (HO) catalyzes the oxidative degradation of heme utilizing molecular...