Báo cáo khoa học: " mechanical determination of the constituents of german substantive compounds" pot

Báo cáo khoa học: "Mechanical Translation and the Problem of Multiple Meaning" pdf

... uncorrelativity of the random force is the shortness of its time of the correlation as compared with the time of the relaxation of the velocity for the large Brownian particles (large frequency of the ... MECHANICAL TRANSLATION In the first works on the theory of the Brown- ian movement (see also ) the values of the velocity of the particle in the various moments of the time were assumed to ... expressed by the formula of the Boussinet, then the assumption about the random force will lead, in particular, to the results of the work. The physical reason of the assumption about the uncorrelativity...

Báo cáo khoa học: " mechanical determination of the constituents of german substantive compounds" pot

... of compounds by means of the mechanical identification of their constituents. This would result in a welcome reduction of the size of the mechanical memory. It is true that the matching of ... inferred from the meanings of the target equivalents of both their constituents, then we enter the smaller one of the two groups of SC into the memory unless the constituent or constituents ... Information Required. The solution suggested in the preceding pages for the mechanical determination of the constituents of all substantive compounds indi- cates the type of qualitative and quantitative...

Tài liệu Báo cáo khoa học: MicroRNA-23a promotes the growth of gastric adenocarcinoma cell line MGC803 and downregulates interleukin-6 receptor pdf

... containing the mutations of the miR-23a binding site (Fig. 4A). It was shown thatmiR-23a ASO or pcDNA3 ⁄ pri-23a did not affect the intensity of EGFP fluorescence in the vector bearing the mutant of the ... with the first potential binding site of the IL6R mRNA 3¢ UTR. (A) The three EGFP reporter vectors bear-ing mutations of the miR-23a seed region binding site are shown. The arrows indicate the ... confirmed the active role of miR-23a in the growth promotion of malignant cells. The fundamental function of miRNAs is to regulatetheir targets by direct cleavage of mRNA or by inhibi-tion of protein...

Tài liệu Báo cáo khoa học: Inorganic phosphate regulates the binding of coﬁlin to actin ﬁlaments pdf

... actin protomers locatedin the vicinity of the barbed end of the filament, pro-ducing an ATP or ADP–Pi cap at this end. Because of the presence of this cap at the barbed end the criticalconcentration ... pertinent to the regulation of actin dynamics in the cell.ResultsFluorescence measurements of the effect of Pion the rate of cofilin binding to TRC–F-actinA convenient way to study the binding of cofilin ... inhibitory effect of Pi on the subtilisin digestionindicates stabilization of the D-loop.Monitoring the binding of cofilin to F-actin bylimited proteolysis The effect of Pi on the binding of cofilin...

Tài liệu Báo cáo khoa học: Final steps in the catabolism of nicotine Deamination versus demethylation of c-N-methylaminobutyrate doc

... may enter the citric acidcycle completing the catabolism of the pyrrolidine moiety of nicotine.Expression of the genes of these enzymes was dependent on the presence of nicotine in the growth ... expression of these genesdepends on the presence of nicotine in the growthmedium and we have determined the enzyme activities of the proteins. Our results demonstrate the presence of two pathways of ... RT-PCR analysis of transcripts. (A) Schematic representation of the pAO1 gene and ORFcluster ﬂanked by Tn554 and DTn. The cluster consists of the pmfR gene, encoding the regulator of the purU-mabO-folD...

Tài liệu Báo cáo khóa học: Further insights into the assembly of the yeast cytochrome bc1 complex based on analysis of single and double deletion mutants lacking supernumerary subunits and cytochrome b pdf

... antibodies to the subunits of the yeast bc1complex indicated on the left side of the blots. The Westernblots are shown in panels A and B and the relative amounts of each of the subunits determined ... mutantstrain. However, the amounts of core protein 1 and coreprotein 2 were relatively unaffected. Therefore, the absence of subunit 6 appeared to alter the rates of processing of two of the redox subunits ... encoded in the nucleus, synthesized by cytosolicpolysomes, and then imported into mitochondria, therebyreaching their ﬁnal location in the inner membrane [17]. The similarities of the yeast...

Tài liệu Báo cáo khoa học: cN-crystallin and the evolution of the bc-crystallin superfamily in vertebrates pdf

... with the familiar pattern of expression of the principally embryonic cA–F genes in the rodentlens [41,47]. The absence of expression in outer layers of the lens contrasts with the expression of ... encodes the ﬁrst two structural motifs, and hence the N-ter-minal domain of the protein, just as in the genes forcS and cA–F. However, the second half of the genehas the structure of a b-crystallin ... polypeptide capable of completing the C-terminal domain of the protein.Currently there is no evidence for expression of canonical cN in primates. This leaves open the ques-tion of whether the gene for...

Tài liệu Báo cáo khoa học: Oxygen tension regulates the expression of a group of procollagen hydroxylases docx

... the question arisesconcerning the mechanisms underlying the orchestratedexpression of these enzymes by the oxygen tension. The ﬁndings that the effect of hypoxia on the geneexpression of the ... 1 : 1000) of a cDNA generated from the pooled RNA of the normoxic (control) cultures (at the different time points) of the respective experimental series(standard cDNA). Analysis of the individual ... clear twofold increase of PDI mRNA,a more moderate increase of the mRNAs for prolylhydroxylases, and did not increase the mRNA abundance of the other enzymes.DiscussionOur data show that the...

Tài liệu Báo cáo khoa học: Proteasome involvement in the degradation of the Gq family of Ga subunits pptx

... alsoobserved in the rate of degradation of the remainingmutant protein (20% left of the protein) vs. the wildtype (40% left of the protein) at 3 h of chase(Fig. 7A,B). We also analyzed the rate of degradation of ... Ga16and Gaqsubunits. Therefore the lack of change in the rate of degradation cannot be due to lack of receptor-activa-tion of the alpha subunits.Given that the activation of G proteins by ligand-stimulated ... a fast rate of degradation. The results impli-cate a prominent role for the proteasome pathway indown regulation and basal turnover of the proteins. The rate of degradation of the Gqproteins...

Tài liệu Báo cáo khoa học: Multidentate pyridinones inhibit the metabolism of nontransferrin-bound iron by hepatocytes and hepatoma cells docx

... of the anemia with bloodtransfusions. The contribution of plasma NTBI to the toxicity associated with Fe overload in these disorders isuncertain, as is the form of NTBI. Signiﬁcant levels of NTBI ... chelators on the uptake and fate of NTBI and to investigate the potential of these chelators for therapeutic use in Fe overload diseasesand cancer chemotherapy. Desferrioxamine (DFO), the only chelator ... is limited by the size of an intracellular chelatable Fe pool or permeability of the Fe–chelator complex.In view of the similar efﬁcacy of the multidentatepyridinones to DFO, further experiments...

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