... benzo [a] pyrene-2¢-deoxyguanosineadducts affects DNA methylation by SssI and HhaI DNAmethyltransferasesOksana M. Subach1, Diana V. Maltseva1, Anant Shastry2, Alexander Kolbanovskiy2,Saulius Klimasˇauskas3, ... The B [a] P-DNA adducts also affect the function of humantopoisomerase I by alteration of DNA cleavage patterns[20]. The greatest disturbance of DNA cleavage iscaused by the (+)-trans-B [a] P-N2-dG ... Wyszynski MW, Gabbara S, Kubareva EA, RomanovaEA, Oretskaya TS, Gromova ES, Shabarova ZA &Bhagwat AS (1993) The cysteine conserved amongDNA cytosine methylases is required for methyl trans-fer,...