... thoseformed under a number of stress conditions [22], butwith the wall of the pore made of both lipid and pro-tein molecules. At the rim of the membrane hole, the two leaflets of the bilayer can make ... the segments thatin the full-length, water-soluble Bax make the fifth and sixth a-helices of the protein structure [25]. However,when these fragments are taken out of their protein context and ... com-plete Bax, the pores made by the Bax peptides are smaller and do not need the concerted action of tBid. These data indicate that the sequences of bothfragments of the hairpin contain the principal...