Báo cáo khóa học: Different associational and conformational

Báo cáo khóa học: Different associational and conformational behaviors between the second and third repeat fragments in the tau microtubule-binding domain pdf

... Different associational and conformational behaviors between the second and third repeat fragments in the tau microtubule-binding domain Katsuhiko Minoura 1 , Tian-Ming Yao 1 , Koji ... of the four -repeat microtubule-binding domain (MBD) moiety in the entire human tau protein (A) and the amino acid sequence of each repeat (B). The region...

Ngày tải lên : 23/03/2014, 12:20

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Báo cáo khoa học: Spatio-temporal distribution of fatty acid-binding protein 6 (fabp6) gene transcripts in the developing and adult zebraﬁsh (Danio rerio) pptx

... according to the tissue from which they were initially isolated, e.g. liver- type fatty acid-binding protein (L-FABP), brain-type fatty acid-binding protein (B-FABP), intestinal-type fatty acid-binding ... lipid-binding protein, intestinal 15 kDa protein, ileal bile acid-binding protein and gastrotropin, reﬂecting the speculations of authors on its intracellular function(s). In vitr...

Ngày tải lên : 07/03/2014, 06:20

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Báo cáo khoa học: Salt-inducible kinase-1 represses cAMP response element-binding protein activity both in the nucleus and in the cytoplasm pdf

... are indicated by underlines. The similarity between SIK1 and SIK2 in domain 3A, the N-terminal half of domain 3, is higher than that in domain 3B, the C-terminal half. (C) The intracellular distribution ... localized less inthenucleusthanthewild-typeSIK1(seethedifference between the ﬁrst and second panels in Fig. 4C). On the other h and, Chimera 2, SIK2, in...

Ngày tải lên : 30/03/2014, 15:20

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Báo cáo khoa học: Missense mutations as a cause of metachromatic leukodystrophy Degradation of arylsulfatase A in the endoplasmic reticulum potx

... recognizing the early epitopes A and B and not with those recognizing the late epitopes C, E and F. Interestingly, mutant ASAs of these two groups are completely retained in the ER. Retention in the ER ... cause ASA deﬁciency. In about half of the examined cases the mutant enzymes are retained in the ER [2,9,10], in the other half, enzymes can leave the ER a...

Ngày tải lên : 07/03/2014, 17:20

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Báo cáo khoa học: Evaluation of potential regulatory elements identi®ed as DNase I hypersensitive sites in the CFTR gene doc

... a proportionate increase in the intensity of the DHS fragments in the control samples. In Fig. 7A the forskolin-treated chromatin shows a relative increase in the intensity of the DHS10a (1716 ... introns 16 and 17 are of similar intensity but the DHS in intron 18 is less evident ( Fig. 5B). In contrast, the DHS in intron 18 is more prominent than those in...

Ngày tải lên : 08/03/2014, 10:20

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Báo cáo khoa học: Isolation of a putative peroxidase, a target for factors controlling foot-formation in the coelenterate hydra docx

... with the tentacles (t) at the distal, and the foot (f) at the proximal end of the animal. The arrow points at peroxidase containing cells lying in the ectoderm of the foot. The diaminobenzidine- stained ... after 35 min by four or ﬁve washes of the gel in H 2 O. The arrows indicate the stained bands in the gel. I is the major peroxidase activity of hydra re...

Ngày tải lên : 08/03/2014, 10:20

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Báo cáo khoa học: Transcriptome proﬁling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet pdf

... Acacb, Acbd6 (acyl-CoA-binding domain containing 6), Scd2 (stearoyl-CoA desaturase 2) or associated genes, Sorbs3 (sorbin and SH3 domain containing 3) and Etnk1_predicted (ethanolamine kinase 1) were down- regulated ... reticulum protein that blocks the processing of sterol regulatory element-binding proteins (SREBPs) by binding to SREBP cleavage-activating protein, thus preventing...

Ngày tải lên : 16/03/2014, 04:20

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Báo cáo khoa học: Quenched hydrogen ⁄deuterium exchange NMR characterization of amyloid-b peptide aggregates formed in the presence of Cu2+ or Zn2+ ppt

... assembled, the N-terminal metal- binding region of the peptide will be in close proximity to both the C-terminal and turn residues, possibly interfering with these regions. This explains how an altered ... assembly and pinpointing the mechanism by which metals guide the path of aggre- gation away from the ﬁbrillar trail. The present investigation assessed how the growth...

Ngày tải lên : 30/03/2014, 01:20

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Tài liệu Báo cáo khoa học: "Different Structures for Evaluating Answers to Complex Questions: Pyramids Won’t Topple, and Neither Will Human Assessors" docx

... turn and marks the appearance of the nuggets. An an- swer string contains a nugget if there is a conceptual match; that is, the match is independent of the partic- ular wording used in the system’s ... according to the vital/okay judgments of assessor a. The differences between the pyramid F-score and the macro- averaged binary F-score correspond to the distinc-...

Ngày tải lên : 20/02/2014, 12:20

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Tài liệu Báo cáo khoa học: Different mechanisms for cellular internalization of the HIV-1 Tat-derived cell penetrating peptide and recombinant proteins fused to Tat docx

... reinforce the argument that the basic domain should be exposed at the surface of the Tat-containing recombinant proteins and call other reasons to explain the differences in the mechanism of internalization ... routes for the Tat CPP and the Tat protein. What might be the reasons underlying the observed differences in cellular uptake between the Tat CPP an...

Ngày tải lên : 21/02/2014, 03:20

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