Báo cáo khoa học: Structural basis for the recognition of co

Báo cáo khoa học: Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lectin ppt

... the corresponding orientation of the side chain of Glu221. The second conformation of the side chain of Glu221, which also adopts two conformations but not correlated with the anomeric form of ... Authors Journal compilation ª 2006 FEBS Structural basis for the recognition of complex-type biantennary oligosaccharides by Pterocarpus angolensis lecti...

Ngày tải lên : 23/03/2014, 11:20

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Báo cáo khoa học: Structural basis for the erythro-stereospeciﬁcity of the L-arginine oxygenase VioC in viomycin biosynthesis docx

... results from conformational control of the enzyme on the side chain rotamer of the bound substrate. For example, in AsnO, a trans con- former is selected for the v 1 torsion angle of bound l-asparagine, ... in active site formation by bordering the substrate bound therein. Active site of VioC Crystals of the substrate complex were obtained by crystallization of...

Ngày tải lên : 16/03/2014, 02:20

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Báo cáo khoa học: Structural basis for the interaction between dynein light chain 1 and the glutamate channel homolog GRINL1A docx

... peptide:protein ratios of 0.5 and 1, corresponding to the free and bound forms, respectively. Their intensities vary according to the population fractions of the free and bound forms of DYNLL1 at the various ... area. Figure 4A shows the 20 lowest-energy conformers from the selected cluster modelled using the Haddock docking calculations. The rmsd values for the 20 l...

Ngày tải lên : 29/03/2014, 09:20

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Báo cáo khoa học: Structural basis for the changed substrate speciﬁcity of Drosophila melanogaster deoxyribonucleoside kinase mutant N64D docx

... comparing the phosphorylation of the natural substrates of the double mutant with the single mutant, it seems that the mutation N45D in the double mutant counteracts the negative effect(s) of the N64D ... ion in the P-loop and Glu172 to the 3¢-OH of the substrate. In the dTTP complex, the phosphates are bound by the LID argi- nines and the 3¢-OH is boun...

Ngày tải lên : 30/03/2014, 20:20

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Tài liệu Báo cáo khoa học: Structural basis for cyclodextrin recognition by Thermoactinomyces vulgaris cyclo⁄maltodextrin-binding protein ppt

... half-buried, and the form of the cleft is markedly different from those of TvuCMBP and EcoMBP. These observations suggest that the structure of the N-domain part and the capacity of the sugar-binding site ... complex, the specificity of the bacterial sugar-binding proteins should be defined in terms not of the affinities for sugars but of whether the protein a...

Ngày tải lên : 19/02/2014, 00:20

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Báo cáo khoa học: Structural basis for substrate recognition by Erwinia chrysanthemi GH30 glucuronoxylanase potx

... chain takes place at the second glycosidic linkage from the MeGlcA side group towards the reducing end of the xylan chain. The elucidation of the three-dimensional structure of the E. chrysanthemi GH30 ... char- acter of the substrate, this Xyl becomes the product of hydrolysis or the nonreducing end of the leaving group. A stereo view of the mode of bi...

Ngày tải lên : 22/03/2014, 16:20

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Báo cáo khoa học: Structural basis for recognition of Co2+ by RNA aptamers pot

... hybridize to the 5¢-end of the loops and propagate to nucleotides involved in the formation of the helix. The strong preference for the 5 ¢-side of the loops in comparison with the 3 ¢ -side may ... Participation of the N7 atom of purines in the organization of the ter- tiary structure of other RNAs has been extensively investigated by the NAIM method...

Ngày tải lên : 16/03/2014, 06:20

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Báo cáo Y học: Structural basis for the inhibitory efﬁcacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

... reduced by the s tacking of O d1 in between the plane of the thiourea moiety and the Ca of G190. Hence, the undefined orientation of the N103 amide Od1 and Nd2 atoms may r eflect the repulsive forces ... electron density for the a mide part of the residue is not very well defined for any of the inhibitor complexes, the inhibitors can still be clearly ranke...

Ngày tải lên : 18/03/2014, 01:20

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Báo cáo khoa học: Structural basis for stereo-speciﬁc catalysis in NAD+-dependent (R )-2-hydroxyglutarate dehydrogenase from Acidaminococcus fermentans pptx

... binding of coenzyme and substrate to the enzyme in its open conformation followed by the closure of the interdomain cleft. In FDH, the structural ordering of the C-ter- minal helix and the rotation ... exit by a reopening of the interdomain cleft. In addition to explaining the functionality of the catalytic triad, the structure–function relationships obta...

Ngày tải lên : 23/03/2014, 13:20

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Báo cáo khoa học: Structural requirements for the apical sorting of human multidrug resistance protein 2 (ABCC2) potx

... demonstrated the transport of conjugated and unconjugated lipophilic anions by MRP2. The absence of MRP2 from the canalicular membrane of human hepatocytes is the molecular basis of the Dubin–Johnson ... N-terminus of MRP2. The N -terminus of MRP2 is located on the extracellular s ide [16], therefore a cDNA was constructed which led to translation of a GFP inse...

Ngày tải lên : 31/03/2014, 09:20

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