... kinase; IL, interleukin; IP3, inositol 1,4,5-triphosphate; IRS, insulin receptor substrate; JAK-STAT, janus kinase-signal transducer and activator of tran-scription, mitogen-activated protein ... is insufficient to accuratelyexplain insulin-stimulated changes in the concentration of intracellularspecies and partitioning of glucosedisposal in skeletal muscle. Insulinpropagates a rather ... acid,argininecatabolismto NO and polyaminesNG, aortaendothelialcellsLow affinity transporter and arginaseshare the control of the fluxesthrough the pathways involvingarginine as a precurser of nitricoxide and polyaminesODE...