Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf

Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf

Báo cáo khoa học: Acute intermittent porphyria – impact of mutations found in the hydroxymethylbilane synthase gene on biochemical and enzymatic protein properties pdf

... identification and expression of exonic mutations in the hydrox- ymethylbilane synthase gene. An initiation codon mis- sense mutation in the housekeeping transcript causes ‘variant acute intermittent porphyria ... were offered screening for the individual mutation. To study the impact of the various mutations on protein structure and functional consequen...
Ngày tải lên : 23/03/2014, 04:21
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Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx

Tài liệu Báo cáo khoa học: A novel splice variant of occludin deleted in exon 9 and its role in cell apoptosis and invasion docx

... roles in the induction of mitochondria-mediated apoptosis and the inhibition of invasion, along with the downregulation of matrix metalloproteinase expression. In addition, by using the calcium indicator ... cells on the bottom of the Matrigel-coated inserts. The number of invasive cells was determined by counting the number of stained cells and then norm...
Ngày tải lên : 18/02/2014, 18:20
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Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx

Tài liệu Báo cáo khoa học: DNA strand exchange activity of rice recombinase OsDmc1 monitored by fluorescence resonance energy transfer and the role of ATP hydrolysis pptx

... function of reac- tion time, at a fixed concentration of protein, by varying nucleotide cofactor conditions. The reaction was the fastest when it contained ATP, where within about 10 0–1 50 s the ... function of OsDmc1 protein concentration (Fig. 4A, lines 2 and 3). How- ever, at concentrations higher than 2.5 lm OsDmc1, there was only an increase in the rate, but no fur...
Ngày tải lên : 19/02/2014, 07:20
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Tài liệu Báo cáo khoa học: "A Multimodal Interface for Access to Content in the Home" pdf

Tài liệu Báo cáo khoa học: "A Multimodal Interface for Access to Content in the Home" pdf

... the pen. In the remote control version, the recog- nizer can also be activated using a button on the remote control. The main section of the search display (Figure 2) contains two panels. The ... used the tablet and then the re- mote control and the other half used the remote 1 Here we report results for the wireless microphone only. Analysis of the...
Ngày tải lên : 20/02/2014, 12:20
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Báo cáo khoa học: Evidence for two different electron transfer pathways in the same enzyme, nitrate reductase A from Escherichia coli potx

Báo cáo khoa học: Evidence for two different electron transfer pathways in the same enzyme, nitrate reductase A from Escherichia coli potx

... reduction and oxidation of the cytochrome hemes with analogues of physiological quinones, using menadione as an analogue of menaquinone and duro- quinone as an analogue of ubiquinone, and comparing ... four kinetic phases in the reduction of the hemes by menaquinol. According to the quinone type used, the two hemes of the cytochrome are probably involved in...
Ngày tải lên : 07/03/2014, 15:20
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Báo cáo khoa học: Distinguishing between different pathways of bilayer disruption by the related antimicrobial peptides cecropin B, B1 and B3 pptx

Báo cáo khoa học: Distinguishing between different pathways of bilayer disruption by the related antimicrobial peptides cecropin B, B1 and B3 pptx

... showed the concentration-dependent effect of bilayer disruption, based on the different thermotrophic phase behaviours and the shapes of the thermal phase- transition curves obtained. The kinetics of ... location, and aggregation state of peptides in their lipid-bound state by analysis of the thermal transitions that these peptide–lipid interactions generate and...
Ngày tải lên : 08/03/2014, 08:20
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Báo cáo khoa học: Modular metabolic control analysis of large responses in branched systems – application to aspartate metabolism potx

Báo cáo khoa học: Modular metabolic control analysis of large responses in branched systems – application to aspartate metabolism potx

... upmod- ulation and downmodulation of the linking intermedi- ate concentration in the range of feasible values, and measurement of this concentration and the correspond- ing values of the rates. ... corresponding modules, the effect of changing supply being much smaller. In addition, the change in one of the demand rates does not severely affect the flux...
Ngày tải lên : 14/03/2014, 23:20
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Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

Báo cáo khoa học: H2O2, but not menadione, provokes a decrease in the ATP and an increase in the inosine levels in Saccharomyces cerevisiae An experimental and theoretical approach pot

... concentration in a metabolic path- way as a function of the kinetic constants of the enzymes involved in that pathway [3]. Application of this method pointed to the inhibition of the rate of synthesis of ... could affect the actual concentration of ATP and hence the rate of synthesis of inosine. It is here assumed that the complex processes of syntheses...
Ngày tải lên : 17/03/2014, 10:20
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Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

Báo cáo khoa học: An E3 ubiquitin ligase, Synoviolin, is involved in the degradation of immature nicastrin, and regulates the production of amyloid b-protein doc

... ER protein (calnexin) and cytoskeleton protein (tubulin) in these cells as the internal control proteins. The calnexin and tubulin levels were found to be similar between these cells, confirming ... ⁄ ))]. These results indicate that a functional deletion of Synoviolin causes a change in the intracellular trafficking of NCT. Effect of Synoviolin on the production...
Ngày tải lên : 23/03/2014, 04:20
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Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc

Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc

... within the range of normality (96 and 134%, respectively). Both parents were asymptomatic. Mutational screening The entire coding region, including exon–intron boundaries and $ 300 bp of the ... one residue following the cleavage site of FXI (P2¢ posi- tion, according to the convention of numbering posi- tion around the scissile bond), thus is part of the activatio...
Ngày tải lên : 23/03/2014, 07:20
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