Báo cáo khoa học: Arthropod nuclear receptors and their role in molting pptx

... establishment of the in vitro binding assayusing receptor proteins, the ligand-binding afﬁnityof ecdysteroids had been measured in tissues and cells[243,244]. The in vitro binding activity of representativeecdysteroids ... retaining theligand-binding activity. They found two high-afﬁnitybinding sites (Kd1= 0.24 nm and Kd2= 3.9 nm). Theremoval of GST had no effect on PonA binding, butaltered DNA binding. ... (2002) Molecularcloning and induction of nuclear receptors from insectcell lines. Insect Biochem Mol Biol 32, 657–667.Y. Nakagawa and V. C. Henrich Arthropod nuclear receptors FEBS Journal...

Tài liệu Báo cáo khoa học: "Detecting Semantic Equivalence and Information Disparity in Cross-lingual Documents" doc

... SPTs (matching more and longer n-grams, with a consequent recall improvement), and DR matching (adding constraints, with a consequentgain in precision). However, the performance in- crease ... Text portions in P1 and P2 that express the samemeaning (bi-directional entailment). In such casesno information has to migrate across P1 and P2, and the two text portions will remain the same;(2) ... portions in P1 that are more informa-tive than portions in P2 (forward entailment). In such cases, the entailing (more informative) portionsfrom P1 have to be translated and migrated to P2 in order...

Tài liệu Báo cáo khoa học: "Paraphrasing Using Given and New Information in a Question-Answer System" docx

... paraphrase for a question containing several clauses of given information and no clauses defining specific attributes of the missing information. Clauses containing information characterized by ... polarity of the text is in question and the finite element indicates this. In this paper the interpretetion of the unknown elements in the question as defined by Krizkova and Helllday is followed. ... the informant to satisfy this want. (ii) [a] it i,~erts knowledge to the informant in that it informs him what the inquirer is interested in (what is on her/his mind) and *...

Báo cáo khoa học: D-strand perturbation and amyloid propensity in beta-2 microglobulin ppt

... intermolecularcross-b interactions in the native protein. On the otherhand, the location of His5 1in the D-strand is intrigu-ing: in native b2m, the His51 side chain points out-wards, although, in the structures ... edgeb-strands, hampering intermolecular backbone interac-tions, and (b) inward-pointing charged side chains thatbecome trapped in the hydrophobic core of the ﬁbrilupon aggregation. Lysines are ... 2349IntroductionIntermolecular cross-b interactions are at the basis ofprotein amyloid aggregation. In the cross-b structure,b-strands belonging to different protein chains associ-ate, giving...

Báo cáo khoa học: Analysis of Lsm1p and Lsm8p domains in the cellular localization of Lsm complexes in budding yeast ppt

... and hybrid Lsm1 and Lsm8 proteins, shedding light on the relative importanceof their various domains in determining their localization and ability tosupport growth. Although no single domain is either ... pro-teins, consisting of a ﬁve-stranded anti-parallel b sheetwhich is involved in intersubunit and protein–RNAcontacts [29,33,34]. Crystal structures and cross-linkingdata have shown that RNA-binding ... proteinsbind RNA, but it is presumed to occur in a similarfashion. Putative RNA-binding residues for buddingyeast Lsm1p and Lsm8p are indicated by asterisks in Fig. 1A,B, and in red in Fig....

Báo cáo khoa học: Characterization of structural and catalytic differences in rat intestinal alkaline phosphatase isozymes pdf

... difference in ligands with an indi-rect interaction was observed: Gln317 in rIAP-I, and Arg317 in rIAP-II. The His317 of hPLAP is known tobe indirectly associated with the M3 site and to main-tain ... alkalinephosphatase; GCAP, germ cell-type alkaline phosphatase; hPLAP, human placental alkaline phosphatase; IAP, intestinal alkalinephosphatase; M1, metal-binding site 1; M2, metal-binding ... human foetal intestinal alkaline phospha-tase. Comparison with the isoenzymes from the adultintestine and human tumour cell lines. Biochem J 211,553–558.36 Smans KA, Ingvarsson MB, Lindgren P,...

Báo cáo khoa học: Dynamin-related proteins and Pex11 proteins in peroxisome division and proliferation doc

... Domain structure of dynamins and dynamin-related proteins(DRPs). GED, GTPase effector domain; MD, middle domain; PH,pleckstrin homology; PRD, proline- and arginine-rich domain.S. Thoms and ... mammalian dynamins, Dynamin1 isneuron-speciﬁc, Dynamin2 is expressed in all tissues and Dynamin3 is found in brain, lung, heart, testis and blood cells.The role of dynamin in clathrin-mediated ... thereby providing the ﬁrst link between aclassical dynamin and an inheritable human disease.Dynamin biochemistry and structure In vitro, dynamin assembles into rings upon dilutioninto buffers...

Báo cáo khoa học: "Balancing User Effort and Translation Error in Interactive Machine Translation Via Conﬁdence Measures" pot

... building phrase-based SMT models. This toolkit involves the esti-mation, from the training set, of different statisti-cal models, which are in turn combined in a log-linear fashion by adjusting ... and Foster, 2003; Ueff-ing and Ney, 2005). In this work, we propose a fo-cus shift in which CMs are used to modify the in- teraction between the user and the system insteadof modify the IMT ... corpus is divided into training, de-velopment and test sets. The main ﬁgures of thecorpus can be seen in Table 1.As a ﬁrst step, be built a SMT system to trans-late from Spanish into English....

Báo cáo khoa học: "Extracting Opinion Expressions and Their Polarities – Exploration of Pipelines and Joint Models" pot

... here have been inspired by informationextraction and semantic role labeling, combinatorialoptimization and structured machine learning.A crucial step in the automatic analysis of opinionis to ... but. In this paper, we ﬁrst implement two strong base-lines consisting of pipelines of opinion expressionsegmentation and polarity labeling and comparethem to the joint opinion extractor and ... recognition and noun chunk extraction.We trained a ﬁrst-order labeler with the discrimi-native training method by Collins (2002) and usedcommon features: words, POS, lemmas in a slidingwindow. In...

Báo cáo khoa học: "Disambiguating Between Generic and Referential “You” in Dialog ∗" ppt

... easy, and the kappa was 100%.We then annotated a total of 42 conversations fortraining and 13 for testing. Different labelers an-notated the training and test sets; none of the au-thors were involved ... Switchboard (Godfrey et al., 1992).tecting the fact that a task is being assigned, and in identifying the owner. While there is an increas-ing body of work concerning addressee identiﬁca-tion (Katzenmaier ... directly and therefore referred tousing a second-person pronoun, as in example (1).1(1)A: and um if you can get that binding point alsomaybe with a nice example that would be helpfulfor Johno and...

Xem thêm