... mice have an increased incidence of systemic lupus erythematosus (SLE), with classical findingsincluding the presence of autoreactive antibodies and glomerulonephritis occurring in a DNase I-level-dependentmanner; ... previously.Proteins were determined using a protein assay kit (Bio-Rad) with BSA as a standard. SDS/PAGE was performed in 12.5% (w/v) gels according to the method of Laemmli[24], and the proteins thus ... Mogi,K.,Kaneko,Y.&Kishi,K.(2001)AmphibianDNasesIarecharacterized by a C-terminal end with a unique, cysteine-richstretch and by the insertion of a serine residue into the Ca2+-binding site. Biochem. J. 357,...