Báo cáo khoa học: Structure, location and interactions of G-quadruplexes pdf
Báo cáo khoa học: Structure, regulation and evolution of Nox-family NADPH oxidases that produce reactive oxygen species pptx
... NH2 and NE in the side chain of this resi-due forming hydrogen bonds with oxygens of the3-phosphate; NH1 and NH2 of Arg105 form hydrogenbonds with the 4-OH and 5-OH of the inositol moiety; and ... a-helices of TPR1 and TPR2 (position 1 of TPR2) and Asn204 in the b-hairpin (position 34 of TPR3), are highly conserved among p67phox and itsrelated proteins (Fig. 14). In addition, substitution of Glu ... magenta, and constitutive interactions by green arrows.(B) Interactions required for activation of Nox1. Interactions in aresting state are indicated by blue arrows; and stimulus-inducedinteractions...
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Báo cáo khoa học: Structure, expression and regulation of the cannabinoid receptor gene (CB1 ) in Huntington’s disease transgenic mice ppt
... increasedexpression of CB1 in the lateral striatum compared t oelsewhere in the brain are present and functional i n youngHD mice. Loss of CB1 or other mRNAs and thedevelopment of NIIs and motor symptoms ... expression of mutant huntingtin and theexact mechanism by which mutant huntingtin alters thefunction of such factors. This work describing the genestructure of CB1 and i ts pattern of expression ... neuro-degeneration of a subpopulation of cells in the basal ganglia.In addition, a reduction in the level of normal huntingtinmay also be detrimental to the survival and function of neurons [4,5].One of the...
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Tài liệu Báo cáo khoa học: Structure determination and biochemical studies on Bacillus stearothermophilus E53Q serine hydroxymethyltransferase and its complexes provide insights on function and enzyme memory doc
... phenolate oxygen of Y51, N of G257 and NE2 of Q53 of the symmetry related subunit. Anotheroxygen atom is held by hydrogen bonding to NE2 of H122 and phenolate oxygen of Y51 of the symmetryrelated ... clashin the position of -CH2OH of l-Ser and the formylgroup of FTHF [12].Mutation of E53 to Q led to a complete loss of THF-dependent cleavage of l-Ser. (Table 1). Km and Vmax of the mutant enzyme ... a-family of pyridoxal 5¢-phosphate-dependent enzymes and catalyzes the reversibleconversion of l-Ser and tetrahydrofolate to Gly and 5,10-methylenetetrahydrofolate. 5,10-Methylene tetrahydrofolate...
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Tài liệu Báo cáo khoa học: Affinity and kinetics of proprotein convertase subtilisin ⁄ kexin type 9 binding to low-density lipoprotein receptors on HepG2 cells docx
... courses and effects of unlabeled ligands and low pH on the dissociation rates of [125I]TC-PCSK9 (A) and [125I]TC-PCSK9-D374Y (B) from HepG2 cells. Binding to equilibrium and removal of unbound ... of lipo-proteins, and there was a corresponding increase in thebinding of [125I]TC-PCSK9 and [125I]TC-PCSK9-D374Y. Second, the extent of specific binding of both[125I]TC-labeled ligands ... internalizedPCSK9–LDLR complexes.Effect of association time on the dissociation of [125I]TC-PCSK9The dependence of dissociation of [125I]TC-PCSK9 and [125I]TC-PCSK9-D374Y on the length of associa-tion time...
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Tài liệu Báo cáo khoa học: Identification and characterization of the transcription factors involved in T-cell development, t-bet, stat6 and foxp3, within the zebrafish, Danio rerio docx
... expression of T-bet has beenseen within a wide variety of tissues and cells in theGinbuna crucian carp [27] and, in mammals, in thelung tissue of mouse and spleen and thymus of human and mouse ... the expression of these genes within humans and mice, of T-betwithin Ginbuna crucian carp [27] and STAT6 inmandarin fish [28] have shown similar widespreadexpression. In the case of STAT6, highest ... of zebrafish t-bet, stat6 and foxp3 were also determined and found to be very simi-lar to their human homologues. Both the human and zebrafish T-bet and Foxp3 genes contained the samenumber of...
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Tài liệu Báo cáo khoa học: Molecular cloning and characterization of soybean protein disulfide isomerase family proteins with nonclassic active center motifs pdf
... S1. Comparison of intron–exon structures of GmPDIL-3a, GmPDIL-3b and orthologs of otherplants.Fig. S2. Multiple amino acid sequence alignment of GmPDIL-3a, GmPDIL-3b and orthologs of otherplants.Fig. ... Identification of the initiation codonsin GmPDIL-3a and Gm-PDIL-3b mRNAs. (A)Schematic representation of the structure of GmPDIL-3a and GmPDIL-3b mRNAs. Theputative ORFs (gray boxes) of GmPDIL-3a and ... by N-glycosylation and the for-mation of disulfide bonds [1]. Disulfide bonds areessential for structural stabilization and for regulation of the functions of many secretory and plasma mem-brane...
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Tài liệu Báo cáo khoa học: SREBPs: physiology and pathophysiology of the SREBP family ppt
... physiology and pathophysiology of theSREBP familyHitoshi ShimanoDepartment of Internal Medicine (Endocrinoglogy and Metabolism), Graduate School of Comprehensive Human Sciences, University of Tsukuba, ... conditions of overnutrition,SREBP-1c expression is elevated, and consequently,the levels of nuclear SREBP-1c protein and lipogenesisare enhanced in the liver and adipose tissues. Intake of energy ... Author Journal compilation ª 2008 FEBSSREBP-1c and lipogenesisThe SREBP family consists of three isoforms: SREBP-1a, SREBP-1c, and SREBP-2. Each isoform has adifferent regulatory mechanism [5–8]....
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Tài liệu Báo cáo khoa học: Identification and characterization of an R-Smad ortholog (SmSmad1B) from Schistosoma mansoni pdf
... properties of SmSmad1 and SmSmad1B asdescribed above. However, in the presence of SmSmad4 and the active mutant form of TbRI, both SmSmad2 and SmSmad4 interacted with GCN5, indicating theformation of ... Drosophila MAD and the vertebrate Smad1,Fig. 1. Structure of the SmSmad1B gene, cDNA and protein. (A) Schematic representations of the SmSmad1B gene, cDNA and protein and the amino acid sequence of SmSmad1B ... Fantappie2,Francisco M. B. Oliveira2 and Philip T. LoVerde1,21 Department of Microbiology and Immunology, School of Medicine and Biomedical Sciences, State University of New York, NY, USA2 Southwest...
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Tài liệu Báo cáo khoa học: Topology, tinkering and evolution of the human transcription factor network doc
... the function and structure of TFs fromavailable information. From a structural point of view,the overabundance of self -interactions is associatedwith a majority group of 55% of basic helix–loop–helix ... ParisiD (2004) Defining and identifying communities in net-works. Proc Natl Acad Sci USA 101, 2658–2663.67 Newman M (2002) Random graphs as models of net-works. Handbook of Graphs and Networks (Bornholdt, ... cut-off kc.By using this algorithm, both hubs and connectors amonghubs are retained.AcknowledgementsThanks to Dr J. Aldana-Montes and members of Kha-os group research of the University of...
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Tài liệu Báo cáo khoa học: Antifungal effects and mechanism of action of viscotoxin A3 docx
... >, of (––) DPH and (ÆÆÆÆ) TMA-DPH incorporated into spores of F. solani in the absence of VtA3(n) and in the presence of 1.5 lM VtA3(s )and3 lM VtA3(n). Insert in (B) shows the evolution of ... targets and the mechanism of action of vis-cotoxin isoform A3(VtA3). We describe a detailed study of viscotoxininteraction with fungal-derived model membranes, its location inside spores of ... potential and volume homeostasis of mitochondria. Cell 91, 627–637.27 Haugland RP (1996) Handbook of Fluorescent Probes and Research Chemicals, 6th edn. Molecular Probes,Inc, Eugene, OR.28 Chandra...
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Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiđề thi thử THPTQG 2019 toán THPT chuyên thái bình lần 2 có lời giảiGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọPhát triển mạng lưới kinh doanh nước sạch tại công ty TNHH một thành viên kinh doanh nước sạch quảng ninhPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu về mô hình thống kê học sâu và ứng dụng trong nhận dạng chữ viết tay hạn chếĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Chuong 2 nhận dạng rui roQuản lý nợ xấu tại Agribank chi nhánh huyện Phù Yên, tỉnh Sơn La (Luận văn thạc sĩ)BT Tieng anh 6 UNIT 2Giáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtchuong 1 tong quan quan tri rui roNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtTrách nhiệm của người sử dụng lao động đối với lao động nữ theo pháp luật lao động Việt Nam từ thực tiễn các khu công nghiệp tại thành phố Hồ Chí Minh (Luận văn thạc sĩ)BÀI HOÀN CHỈNH TỔNG QUAN VỀ MẠNG XÃ HỘIChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015