... section and scheme of the coronal section at E14.5 in (F). (A) At E11.5, HSF2 is expressed in forebrain, midbrain and in hindbrain except for the midbrain, hindbrain midline. Surprisingly, the ... before and after birth in mouse brains[122,124]. No HSF4 DNA-binding activity wasreported in the developing mouse brain so far. How-ever, Hsf4b is expressed in the adult mouse brain,including ... absence of HSF4, histone H3K9methylation is induced and HSF1 binding is reduced,indicating that HSF4 facilitates HSF1 binding viachromatin remodelling. Heat shock genes are notHSF4 targets,...