Báo cáo khoa học: Transcript proﬁling during the early development of the maize brace root via Solexa sequencing pot

... manner.Comparison of the maize brace root and primary root transcript proﬁlesTo determine the differentially expressed transcriptsinvolved in the maize brace root and primary root development, we compared the ... in the brace root tissue. For the rest of the categories, the tran-script abundances in the brace root were higher thanthat in the primary root. In the 55 annotated tags in the primary root ... development of the maize brace root was acquired by deep sequencing. For the ﬁrst time, we have comprehensively characterized the molecular basis of the physiological processes during maize brace root...

Báo cáo khoa học: Transcript proﬁling reveals diverse roles of auxin-responsive genes during reproductive development and abiotic stress in rice pdf

... differentially during panicle development in rice in this study. A very highlevel of expression of OsARF11, a putative ortholog of MONOPTEROS, during early panicle development, representing the stages of ... inat least one of the stages of panicle or seed development as compared with vegetative development stages. Fur-thermore, the genes expressed differentially at any stage of panicle development ... study the expression proﬁles of GH3, Aux ⁄ IAA,SAUR and ARF gene family members during various stages of development and abiotic stress conditions, the probe sets Transcript proﬁling of auxin-responsive...

Báo cáo khoa học: Transcriptome proﬁling analysis reveals multiple modulatory effects of Ginkgo biloba extract in the liver of rats on a high-fat diet pdf

... discovery rate = 0.01) using the softwaresam 2.20 [32]; (b) the standard deviation of the log ratios in the control group was > 1; or (c) the absolute value of the log ratio was > 0.585 ... of the total number of arrays. We furthereliminated gene sets with unreliable expression measures,on the basis of data from group C. Data were excluded if:(a) the signal of log ratios in the ... sterogenesis. The increased expression of Insig2 and the further repression of Hmgcr suggestedthat endogenous cholesterol synthesis was repressed. The upregulation of Nr1h4 and downregulation of Cyp7a1...

Báo cáo khoa học: "Error Proﬁling: Toward a Model of English Acquisition for Deaf Learners" ppt

... and the ResponseGeneration Module (which builds the feedback to the user based on the errors the user has commit-ted). The work described in this paper focuses on the development of one of the ... than the high-level writ-ers with a signiﬁcance of .0083. The compari-son of the low and middle levels to each other, on the other hand, showed that the low-level learnerscommitted more of this ... because the authors had more opportunity tomake errors. We therefore used two dependentvariables in our analysis: the TWE score and the length of the sample, testing the ability of the twocombined...

Báo cáo khoa học: Expression proﬁling reveals differences in metabolic gene expression between exercise-induced cardiac effects and maladaptive cardiac hypertrophy pot

... from the study. The experiments wereapproved by the Animal Experimentation Inspectorate of the Danish Ministry of Justice and the investigation con-forms to the Guide for the Care and Use of ... accordance with these data, we found upregulation of glucokinase (hexokinase 1) in hearts of exercisedrats. Further evidence of enhanced glycolysis camefrom the upregulation of 6-phosphofructo-2-kinase ... supported by the John and Birthe MeyerFoundation, the Danish Heart Foundation (01-1-2-59-22907, 99-1-2-31-22684), the Villadsen Family Founda-tion, the Foundation of 17.12.1981, the University of Copenhagen,...

Báo cáo khoa học: Glycan profiling of urine, amniotic fluid and ascitic fluid from galactosialidosis patients reveals novel oligosaccharides with reducing end hexose and aldohexonic acid residues ppt

... moie-ties of glycosphingolipids. On the basis of the presence of carbohydrate moieties of glycosphingolipids, wespeculate about the potential involvement of a cera-mide glycanase in the catabolism of ... below.Two isomers of the glycan H2were detected. The retention time of the late-eluting H2isomer was identi-cal to that of maltose (Glc(a1–4)Glc; Table 2). The retention time of the early- eluting ... 3%;Table 3). The cause of C1oxidation of the reducingend is unknown. We can exclude the possibility thatthese species were observed due to oxidation of reduc-ing sugars during the chromatographic...

Tài liệu Báo cáo khoa học: P25a ⁄ TPPP expression increases plasma membrane presentation of the dopamine transporter and enhances cellular sensitivity to dopamine toxicity pptx

... mice [28]. The instability of DA at the neutral pH of the cytosol causes the forma-tion of toxic aminochromes, and these species are notformed when DA is protonated at the acidic pH of the storage ... counter. Values are the mean of six replicates. The specific uptake was determined bysubtracting the uptake counts in the absence of inhibitorfrom the uptake counts in the presence of cocaine or S-cita-lopram, ... total concentration of DA and the y axis shows the DA uptake after 10 min. The y axis demonstrates specificuptake, defined as total uptake subtracted the uptake in the pres-ence of the DAT inhibitor...

Tài liệu Báo cáo khoa học: Mixed lineage leukemia: a structure–function perspective of the MLL1 protein ppt

... a picture of how the recruitment of MLL1 can increase the binding of other important transcriptional activators that ulti-mately could result in the synergistic activation of genetranscription. ... observation). In the ternarycomplex, the histone H3 peptide binds in a deep chan-nel that divides a pair of acidic lobes, one of which iscomposed of residues from the SET-I region and the other of residues ... represents the range of possibleconformations that may exist in solution.Consistent with the conformational change hypothe-sis, Southhall et al. [26] observed that addition of othercomponents of the...

Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): evaluation of the biological function of growth-inhibitory factor in the injured and neurodegenerative brain pdf

... in all of these conditions [22]. In the trau-matically injured brain, however, the synthesis of MT1and MT2, as well as the synthesis of GIF, are up-regu-lated by reactive astrocytes in the vicinity ... ﬁneprocesses of these cells. Astrocytic synthesis of GIFis mainly found in the cortex, brainstem and spinalcord [6].Additionally however, there are also consistentreports of neuronal synthesis of GIF, ... partly explaining the vast neuronal lossin the AD brain. Further investigation of the increasedneurotrophic activity of the AD brain revealed that itcorrelated with the loss of a speciﬁc neuroinhibitoryfactor,...

Tài liệu Báo cáo khoa học: Compartmentalization and in vivo insulin-induced translocation of the insulin-signaling inhibitor Grb14 in rat liver pptx

... [6] and inhibits the tyrosine kinase activity of the IR [7]. On the basis of the crystal structure of the tyrosine kinase domain of the IR in complex with the PIR ⁄ BPS domain of Grb14,Depetris ... interaction of Grb14 with the IR is probably the major determi-nant of the insulin-induced membrane translocation of Grb14, several lines of evidence suggest that the associ-ation of Grb14 via its ... we cannot assess whether the kinase activity of the IRs before KCl treatment repre-sents residual activity of receptors with Grb14 bound tothem, the activity of a fraction of receptors lackingbound...

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