... small heat shock proteins hsp27 and aB-crystallin in Parkinson’sdisease. NeuroReport 10, 2273–2276.10 Head MW & Goldman JE (2000) Small heat shock pro-teins, the cytoskeleton, and inclusion ... are found in most celltypes in most organisms, and their expression is upreg-ulated under a range of stress conditions, such as heat, oxidative conditions, pH changes, infection and in many disease ... extension is reduced [25], and introduction ofhydrophobicity into the C-terminal extension ofaA-crystallin results in immobilization of the C-termi-nal extension and reduced chaperone activity...