Báo cáo khoa học: S1 – The genome in the 3rd millennium docx

Tài liệu Báo cáo khoa học: An alternative isomerohydrolase in the retinal Muller cells of a cone-dominant species doc

... contribute toproviding chromophore to melanopsin to maintaintheir light sensitivities. The expression and function ofRPE65c in other cell types in the retina remains to beinvestigated.Earlier ... RPE65c in the inner retina,including Mu¨ller cells, but not in the RPE. Furthermore, double-immuno-staining of dissociated retinal cells using antibodies for RPE65c and gluta-mine synthetase (a ... processinvolving multiple enzymes and retinoid-binding pro-teins between photoreceptors and retinal pigment epi-thelium (RPE); it is essential for maintaining normalvision [3,4]. The key step in...

Tài liệu Báo cáo khoa học: Metabolic gene switching in the murine female heart parallels enhanced mitochondrial respiratory function in response to oxidative stress pdf

... 2007)doi:10.1111/j.1742-4658.2007.06051.x The mechanisms underlying increased cardioprotection in younger femalemice are unclear. We hypothesized that serine-threonine protein kinase(protein kinase B; Akt) triggers ... Cooksey RC, McClain DA,Litwin SE et al. (2002) Insulin signaling coordinatelyM. F. Essop et al. Metabolic gene switching in murine female heartFEBS Journal 274 (2007) 527 8–5 284 ª 2007 The Authors ... insights into thisinteresting question.Conclusions In summary, we have identiﬁed a novel metabolicgene switch (decrease in fatty acid utilization,increase in glucose utilization) in the murine...

Tài liệu Báo cáo khoa học: Osmosensing and signaling in the regulation of mammalian cell function docx

... integrin-dependentcell volume sensing and signaling integrates into the overall context of insulin signaling. Similarly, sensingof glutamine-induced hepatocyte swelling by integrinsfeeds into ... hepatocyte swelling [12,13], insu-lin-induced hepatocyte swelling is registrated by the integrin system, leading to a Src-dependent activationof the p38-type MAPK and thereby inhibition ofautophagic ... the integrin system asone major sensor of hepatocyte swelling [1 2–1 4].Integrin-inhibitory peptides exhibiting an arginine-gly-cine-aspartic acid (RGD) motif abolish hypoosmoticosmosignaling...

Tài liệu Báo cáo khoa học: An intermediate step in the evolution of ATPases – a hybrid F0–V0 rotor in a bacterial Na+ F1F0 ATP synthase pdf

... of the c ring, respectively. The C-terminal helices show a clear handedness, and twoof the rings face in the opposite direction in the membrane to the other two, forming the same patternas in ... charges on the ring and thus keeps the ring in place [3 4–3 6]. How-ever, the system is not stiff but instead the ring idles in front of the positive charge. This site is accessible to the outside, ... of the ion-binding site. Therefore, the c ring of A. woodii hasonly 10 membrane-buried negative charges that areessential for binding the ion and also for the rotationalmechanism of the ring....

Tài liệu Báo cáo khoa học: Bone morphogenetic proteins in the early development of zebraﬁsh pptx

... Follistatin, Chordin and Noggin[12]. These proteins are antagonists of BMP and othermembers of the TGF-b family, binding to and inhibit-ing these signaling molecules from binding to theirreceptors ... theirreceptors in the extracellular space, thus inhibiting ven-tralizing activities. Of these proteins, Chordin has along-range effect. In Xenopus, expression of the chordingene is localized to the dorsal ... 274 (2007) 296 0–2 967 ª 2007 The Author Journal compilation ª 2007 FEBS 2963Mutations in BMP regulatorsMutation in the BMP binding protein Chordin causes the dino mutant [23,24]. dino mutants show...

Tài liệu Báo cáo khoa học: Integral membrane proteins in the mitochondrial outer membrane of Saccharomyces cerevisiae docx

... material (P). Proteins were then analyzed by immunoblotting afterSDS ⁄ PAGE using antisera against the matrix-located mtHsp70, the membrane protein porin and GFP.Integral proteins in the mitochondrial ... membraneprotein with its N-terminal FAD-binding domainfacing the intermembrane space. This topology wouldenable Gut2 to transfer of electrons to Nde1 in the intermembrane space [32].Alo1 catalyses the ... most of the proteincomponents are integral in the membrane, most of these mitochondrial pro-teins behave as if they have a-helical transmembrane domains, rather thanb-barrels. These proteins are...

Tài liệu Báo cáo khoa học: "Automatic error detection in the Japanese learners’ English spoken data" pdf

... categories.Method C * there is telephone and the books on the desk. Eb: The word in the beginning of the part which should be replaced. Ee: The word in the middle or the end of the part which ... word and the one preceding/ the targeted word and the one following/ the targeted word and the two preceding/ the targeted word and the two fol-lowing), and the first and last letters of the word. ... i.e., the targeted word and the two preceding and follow-ing words, their word classes, their root forms, five combinations of these (the targeted word, the one preceding and one following/ the...

Tài liệu Báo cáo khoa học: "Reactive Content Selection in the Generation of Real-time Soccer Commentary" pdf

... for the dotted line, which is not the case for the solid line. Also, the peaks are higher for the solid line than dotted. • The area covered by the solid line is larger than that by the dotted, ... modules). The modules an- alyze the data from the Soccer Server, communicate with each other via the shared memory, and then post the results as propositions into the Pool. The Real Time Inference ... Pool that best fits the current state of the game (considering both the situation on the field and the comment currently being made). It then translates the proposition into NL. So far, MIKE...

Tài liệu Báo cáo khoa học: A point mutation in the ATP synthase of Rhodobacter capsulatus results in differential contributions of DpH and Du in driving the ATP synthesis reaction pptx

... This results in a n exchange between the incoming DNA and the corresponding chromosomal DNAwhich is lost in the process. In this work, the GTA exchangedonor was the J1 strain carrying the p Fo39 ... ms(extrapolating the ﬁttin g function when necessary). The ratios of the wild-type derivatives over the mutant, indicating the ratios of the ATPsynthesis rates, are plotted for the exp eriments in the ... byplotting the ratio of the ﬁ tting f unctions of wild-type overmutant, either in the presence or in the absence of a Du,asshown in Fig. 3 C. In the presence of a Du, the differencebetween the...

Tài liệu Báo cáo khoa học: "Some Pragmatic Issues in the Planning of Definite and Indefinite Noun Phrases" potx

... kinds of definite referring actions: one is that in which the precondition is mutual knowledge of a descrip- tion. and the other in which there is mutual knowledge of a plan incorporating the ... action, the speaker and he=rer mutually believe that executing plan P will result in the hearer acquiring the required information, but, since only the hearer is actually executing the plan, the ... result in identification of the intended referent, and in the case of the S[ action, the plan is simply to do nothing, because the referent of the term is already mutually known. This is not the...

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