Báo cáo khoa học: Metabolism of N-methyl-amide by cytochrome P450s Formation and characterization of highly stable carbinol-amide intermediate pdf
Báo cáo khoa học: Metabolism of N-methyl-amide by cytochrome P450s Formation and characterization of highly stable carbinol-amide intermediate pdf
... 2011 FEBS Metabolism of N-methyl-amide by cytochrome P450s Formation and characterization of highly stable carbinol-amide intermediate Lionel Perrin1,2,3,4, Nicolas Loiseau5, Franc¸ois Andre´3,4 and ... 0.60 Formation and characterization of stable carbinol-amide L. Perrin et al.2170 FEBS Journal 278 (2011) 2167–2178 ª 2011 The Authors Journal compilation ª 2011 FEBS of H2O and CH2O) and ... tothe R1R2NCH2OH intermediate (carbinol-amine or carbinol-amide) .Energies and free enthalpies are given in kcalÆmol)1. Formation and characterization of stable carbinol-amide L. Perrin...
- 12
- 353
- 0
Tài liệu Báo cáo khoa học: Phenol hydroxylase from Acinetobacter radioresistens S13 Isolation and characterization of the regulatory component docx
... acceptors such as cyto-chrome c and Nitro Blue Tetrazolium. The molecularmass of PHI was determined to be 10 kDa by SDS/PAGE, 8.8 kDa by MALDI-TOF spectrometry and 18 kDa by gel-permeation. This finding ... ratio of 1. Asterisks and broken line: data and fitting with PHI/PHO ratio of 2.Fig. 5. Effect of PHI on the flavin fluorescence of the complex PHR–PHO. Dotted line: fluorescence emission spectrum of ... were recorded from 260 to 190 nm at aspeed of 50 nmÆmin)1, band-width of 1.0 nm, and aresolution of 0.1 nm in the temperature range between10 °Cand70°C, after preincubation for 10 min at...
- 7
- 514
- 0
Tài liệu Báo cáo khoa học: Neuronal growth-inhibitory factor (metallothionein-3): reactivity and structure of metal–thiolate clusters* doc
... characterized by a conserved array of 20 cysteines and the absence of His and aromatic amino acids. MT3 contains 68amino acids with 70% sequence identity to the MT1 and MT2 (MT1 ⁄ 2) isoforms. The ... theisostuctural replacement of Zn(II) with Cd(II), by monitoring the peptide structure and the flexibility of Zn(II) and Cd(II) by NMR spectroscopy. Anotherinteresting (and to my knowledge not yet ... [32]. Indeed, exposure of Cu(I)4-Zn4MT3 to air resulted in the slow formation of adisulfide linkage by cysteine oxidation of the a-domain and a concominant release of one Zn ion, but the...
- 10
- 569
- 0
Tài liệu Báo cáo khoa học: Poly(silicate)-metabolizing silicatein in siliceous spicules and silicasomes of demosponges comprises dual enzymatic activities (silica polymerase and silica esterase) doc
... displacement of p-aminophenol and formation of a (alkoxyl)-monosilane. This reac-tion is facilitated by hydrogen bonding between the imidazole nitro-gen of the conserved histidine (His) and the ... (Asn) and serine (Ser) [4,12]. In the active center of silicatein, thehydroxyl group of Ser26 and the imidazole of His165(catalytic diad) have been shown to play key roles inthe condensation of ... cleav-age of one of the silica ester bonds, the concentration of the released product p-aminophenol was determinedat a wavelength of 300 nm, which is in the trailingedge of the main absorption bands...
- 9
- 576
- 0
Tài liệu Báo cáo khoa học: Structural insights into the substrate specificity and activity of ervatamins, the papain-like cysteine proteases from a tropical plant, Ervatamia coronaria ppt
... rounds of positional refinement, fitting, and introduction of watermolecules and SO42), followed by manual fitting of themodel by quanta (Accelrys Inc.), led to an R-factor of 19.78% and Rfree of ... understanding of the genericprinciple of catalysis for this family of proteases.Results and DiscussionFold of ervatamin-AThe overall structure and fold of ervatamin-A is simi-lar to that of ... exemplified by a comparison of the cata-lytic-site structure and characteristics of cathepsin B and papain. pH-dependent kinetics of the reactions of cathepsin B from bovine spleen and from rat...
- 14
- 634
- 0
Tài liệu Báo cáo khoa học: The role in the substrate specificity and catalysis of residues forming the substrate aglycone-binding site of a b-glycosidase docx
... binding of the second glucose unit of oligosaccharidic aglycones and also of the initial portion of alkyl-type aglycones. None of the residuesinvestigated interacted with the terminal portion of ... details about the role of different resi-dues of the aglycone-binding site in the stabilization of ESà and the interdependence between the binding of aglycone and the positioning of glycone in subsite ... formed by T194, F198, F205 and F466in ZmGlu1, and by V196, L203 and S462 in SbDhr1.These residues correspond to C170, L174, H181 and A411 in BglB, which, together with Y196, N223, E225,Q316 and...
- 12
- 731
- 0
Tài liệu Báo cáo khoa học: "Collecting a Why-question corpus for development and evaluation of an automatic QA-system" pdf
... selection of natural questions. Thearticles varied in topic, degree of formality and theamount of details; from ”Horror film” and ”Christ-mas worldwide” to ”G-Man (Half-Life)” and ”His-tory of London”. ... were grouped into groups of 5.Each HIT consisted of 5 assignments, and a $0.05reward was offered for each HIT.QRepHIT required the least amount of design and trials, and workers were delighted ... time-consuming process and not ap-plicable within efficient development of sys-tems. Automatic evaluation requires a cor-pus of questions and answers, a definition of what is a correct answer, and a way...
- 9
- 610
- 1
Báo cáo khoa học: Protein transport in organelles: The composition, function and regulation of the Tic complex in chloroplast protein import pptx
... constituent of the Tic motor complex(see below).The present minireview provides a short description of recent advances in the understanding of the chan-nel-, motor- and regulatory components of the ... phenotype can be complemented by overexpression of the other isoform. However, analysis of double knockouts of both Hsp93 homologues didnot result in the identification of double homozygotes,establishing ... high efficiency of protein import, additional regulatory subunitshave been developed that sense, and quickly react to, signals giving infor-mation about the status and demand of the organelle....
- 11
- 491
- 0
Báo cáo khóa học: Surface nucleolin participates in both the binding and endocytosis of lactoferrin in target cells potx
... this binding. Some of theseFig. 10. Prediction of nucleolin-binding sites in human lactoferrin (hLf).Sequences of the N2 and C2 domains of hLf, bovine lactoferrin (bLf) and human transferrin ... site of the N-terminal lobe of human and bovine lactotransferrins. Importance of the glycanmoiety and of the non-covalent interactions between the N- and C-terminal lobes in the stability of the ... potential to interact with nucleolin.The stable binding of Lf to cells could mostly becoordinated on the one hand by nucleolin and on the otherhand by surface proteoglycans, which are able...
- 15
- 509
- 0
Báo cáo khoa học: "Deciphering Foreign Language by Combining Language Models and Context Vectors" pdf
... an active set of translationcandidates. Based on the assumption that some of the active candidates and their respective probabili-ties are already correct, we induce new active candi-dates. ... InitializationLet NCbe the maximum number of candidates persource word we allow, Ve and Vfbe the target/sourcevocabulary and r(e) and r(f) the frequency rank of a source/target word. Each word ... sizes of about500 words and achieve a performance of around20 BLEU compared to 70 BLEU obtained by a sys-tem that was trained on parallel data. Our work usesthe same training criterion and...
- 9
- 352
- 0
Từ khóa: báo cáo khoa học mẫubáo cáo khoa học y họcbáo cáo khoa học sinh họcbáo cáo khoa học nông nghiệpbáo cáo khoa học lâm nghiệpbáo cáo khoa học thủy sảnchuyên đề điện xoay chiều theo dạngNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namNghiên cứu tổ chức pha chế, đánh giá chất lượng thuốc tiêm truyền trong điều kiện dã ngoạiMột số giải pháp nâng cao chất lượng streaming thích ứng video trên nền giao thức HTTPGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEPhối hợp giữa phòng văn hóa và thông tin với phòng giáo dục và đào tạo trong việc tuyên truyền, giáo dục, vận động xây dựng nông thôn mới huyện thanh thủy, tỉnh phú thọTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngĐịnh tội danh từ thực tiễn huyện Cần Giuộc, tỉnh Long An (Luận văn thạc sĩ)Tìm hiểu công cụ đánh giá hệ thống đảm bảo an toàn hệ thống thông tinThơ nôm tứ tuyệt trào phúng hồ xuân hươngGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 15: Tiêu hóa ở động vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM