Báo cáo khoa học: Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration ppt

Báo cáo khoa học: Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration ppt

Báo cáo khoa học: Reducing expression of NAD+ synthesizing enzyme NMNAT1 does not affect the rate of Wallerian degeneration ppt

... dowregulation of NMNAT1 expression does not affect the rate of axon degeneration in vitro. Discussion These data indicate that complete NMNAT1 gene inactivation is incompatible with the normal develop- ment ... Journal compilation ª 2011 FEBS 2679 Reducing expression of NAD + synthesizing enzyme NMNAT1 does not affect the rate of Wallerian de...
Ngày tải lên : 22/03/2014, 16:20
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Báo cáo khoa học: Caenorhabditis elegans metallothionein isoform specificity – metal binding abilities and the role of histidine in CeMT1 and CeMT2 potx

Báo cáo khoa học: Caenorhabditis elegans metallothionein isoform specificity – metal binding abilities and the role of histidine in CeMT1 and CeMT2 potx

... apparent additivity of the stoichiometries of the complexes ren- dered by the separate moieties of CeMT1 and CeMT2, the summation of their CD spectra did not give rise in any case to spectra close to those of the entire ... for the native and recombi- nant Cd(II)–CeMT2 isoform [16,20]. The slight blue- shift of the spectrum of Cd 6 Zn 1 –CeMT1 in relation to th...
Ngày tải lên : 07/03/2014, 02:20
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Báo cáo khoa học: A novel metallobridged bis(b-cyclodextrin)s fluorescent probe for the determination of glutathione doc

Báo cáo khoa học: A novel metallobridged bis(b-cyclodextrin)s fluorescent probe for the determination of glutathione doc

... which influences the flu- orescence intensity. Therefore, the influence of the vol- ume of buffer was measured. Because the volume of buffer added (1.00–3.00 mL) had little effect on the fluorescence ... fluorophores. The compound could be dis- solved in aqueous solution and showed high binding ability because of the two adjacent bis(b-CD)s. Because of the conformation o...
Ngày tải lên : 07/03/2014, 05:20
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Báo cáo khoa học: Cofactor-independent oxygenation reactions catalyzed by soluble methane monooxygenase at the surface of a modified gold electrode pot

Báo cáo khoa học: Cofactor-independent oxygenation reactions catalyzed by soluble methane monooxygenase at the surface of a modified gold electrode pot

... maintained. Detection of the products of substrate oxygenation by the adsorbed MMOH was achieved by holding the potential at )0.5 V for 30 min in the presence of substrate and then removing the liquid (50 ... fitted with GPES software. The surface of the 4-mm diameter gold electrode (Oxford Electrodes) was modified by cycling the electrode at reducing potentials in th...
Ngày tải lên : 17/03/2014, 09:20
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Báo cáo khoa học: "PCFGs, Topic Models, Adaptor Grammars and Learning Topical Collocations and the Structure of Proper Names" ppt

Báo cáo khoa học: "PCFGs, Topic Models, Adaptor Grammars and Learning Topical Collocations and the Structure of Proper Names" ppt

... consists of the set of trees with whose root node is labelled X and whose ith child is a member of T B i . 1149 The set of trees generated by the CFG is T S , where S is the start symbol, and the ... but it has the advantage that the LDA distributions map straight-forwardly onto PCFG nonterminals). The terminals W of the CFG consist of the vo- cabulary V of...
Ngày tải lên : 23/03/2014, 16:20
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Báo cáo khoa học: "Adding Syntax to Dynamic Programming for Aligning Comparable Texts for the Generation of Paraphrases" potx

Báo cáo khoa học: "Adding Syntax to Dynamic Programming for Aligning Comparable Texts for the Generation of Paraphrases" potx

... (Milan Theater) and is not at the beginning of that constituent. Finally, the syntactic depen- dence trace of a word is the path of IOB values from the root of the tree to the word itself. The last ... used to guide the align- ment. Starting from the bottom right entry of the matrix, we go to the matrix entry from which the value of the current cell is...
Ngày tải lên : 31/03/2014, 01:20
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Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

Tài liệu Báo cáo khoa học: Homologous expression of the nrdF gene of Corynebacterium ammoniagenes strain ATCC 6872 generates a manganese-metallocofactor (R2F) and a stable tyrosyl radical (Y•) involved in ribonucleotide reduction ppt

... function of man- ganese in the transcriptional regulation of the nrd operon [35] may not be considered in the light of the results obtained in the present study. Rather, the involvement of manganese ... to the catalytic site of the R1E subunit. As reported in the Results, upon completion of substrate conversion, the radical is then rapidly passed back from t...
Ngày tải lên : 15/02/2014, 01:20
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Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

Tài liệu Báo cáo khoa học: Tissue expression and biochemical characterization of human 2-amino 3-carboxymuconate 6-semialdehyde decarboxylase, a key enzyme in tryptophan catabolism pptx

... mark the boundary of the predicted substrate-binding pocket, reveals that some of them are conserved in the inac- tive isoform (i.e. Trp191 and Phe294). Even though the precise role of these ... human ACMSD. The presence of the metal- locofactor in human ACMSD might also be inferred by our study on the enzyme pH dependence, showing that the increase of the concen...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt

Tài liệu Báo cáo khoa học: Differential expression of duplicated LDH-A genes during temperature acclimation of weatherfish Misgurnus fossilis Functional consequences for the enzyme ppt

... quantitative strategy to offset the lack or excess of kinetic energy (as a measure of temperature) and its effect on enzyme activity. Alternatively, we know of a number of examples of qualitative strategies, ... considered in the context of the relevance for the performance of metabolic networks, because the theory of metabolic control analysis states that enzyme...
Ngày tải lên : 19/02/2014, 02:20
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Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

Tài liệu Báo cáo khoa học: Altered expression of CD1d molecules and lipid accumulation in the human hepatoma cell line HepG2 after iron loading pptx

... unable per se of regulating the expression of ICAM-1, and other immune recognition molecules other than Nor3.2-reactive CD1d. To our knowledge, iron loading does not regulate members of the MHC class ... cytometry revealed that the inhibition of cell growth was due to a decrease in the percentage of cells in the S and G2 ⁄ M phases of the cell cycle (Fig. 3B). In...
Ngày tải lên : 19/02/2014, 16:20
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