Báo cáo Y học: Thiol-modifying inhibitors for understanding squalene cyclase function pdf

Báo cáo Y học: Thiol-modifying inhibitors for understanding squalene cyclase function pdf

Báo cáo Y học: Thiol-modifying inhibitors for understanding squalene cyclase function pdf

... site-directed mutagenesis; squalene cyclase; thiol reagents. Oxidosqualene cyclases (OSCs) and squalene- hopene cyclases (SHCs) are key enzymes in triterpenoid biosynthesis: they transform acyclic isoprenoid ... Novara, Italy The function of squalene- hopene cyclase from Alicycloba- cillus acidocaldarius was studied by labelling critical cysteine residues of the enzyme, either native...
Ngày tải lên : 17/03/2014, 23:20
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Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

Báo cáo y học: "Clinical Strategy for the Management of Solid Pseudopapillary Tumor of the Pancreas: Aggressive or Less"

... analysis of sol- id-pseudopapillary tumor of the pancreas: report of 15 cases. Hepatobilliary Pancreat Dis Int. 2008;7(2):196-200. 10. Yu CC, Yeh CN, Hwang TL, Jan YY. Clinicopathological study ... routinely performed to rule out pancreatic malignancy. Other- wise, for the patients with pancreatic malignancies, a radical surgery should be the reasonable option for curative therapy. A...
Ngày tải lên : 25/10/2012, 11:40
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Báo cáo y học: "Enhanced surveillance for childhood hepatitis B virus infection in Canada, 1999-2003"

Báo cáo y học: "Enhanced surveillance for childhood hepatitis B virus infection in Canada, 1999-2003"

... laboratories, which were performing confirmatory testing for HB in each jurisdiction, either automatically reported or were contacted regularly for newly identified HB cases, laboratory test results, ... predefined questionnaires for all seven health regions. The notification system was not materially changed during the study period, but augmented throughout by scrutiny of laborat...
Ngày tải lên : 02/11/2012, 11:08
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Tài liệu Báo cáo Y học: Systematic search for zinc-binding proteins in Escherichia coli potx

Tài liệu Báo cáo Y học: Systematic search for zinc-binding proteins in Escherichia coli potx

... 1,6-bisphosphatase aldolase 4 GlyA Serine hydroxymethyltransferase 5 LpdA* (AtpA) Lipoamide dehydrogenase (F1 ATP synthase a subunit) 6 Ppa* (AhpC) Inorganic pyrophosphatase (alkyl hydroperoxide reductase ... BL21. For purification of zinc-binding proteins, cells were lysed in lysis buffer containing 0.2 mgÆmL )1 lysozyme, 0.2 m M phenylmethanesulfonyl fluoride and 1 m M dithiothreitol, follo...
Ngày tải lên : 22/02/2014, 04:20
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Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

Báo cáo Y học: Structural basis for the inhibitory efficacy of efavirenz (DMP-266), MSC194 and PNU142721 towards the HIV-1 RT K103N mutant doc

... namely that they contain a hydrogen-bond donor in wing2. This property is of general importance for the efficacy of the inhibitor. Substitution of the hydrogen-donating amide group for a methylene ... The analysis of the inhibitors HBY 097 in complex with the Y1 88L mutant and 8-Cl TIBO in complex with the Y1 81C mutant, revealed that the retained efficacy of these inhibitors was due...
Ngày tải lên : 18/03/2014, 01:20
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Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx

Báo cáo Y học: A model for recognition of polychlorinated dibenzo-p-dioxins by the aryl hydrocarbon receptor docx

... the mouse aryl hydrocarbon receptor (mAhR). The model allowed us to putatively i dentify the residues responsible for the recognition of polychlorinated dibenzo- p-dioxins (PCDDs) by AhR receptors ... FixL, oxygen binding at the heme binding PAS domain controls the activity of a h istidine kinase domain [12]; and in PYP, a local conformational change occurs once the p-hydroxycinnamoyl cromo...
Ngày tải lên : 24/03/2014, 00:21
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Báo cáo khoa học: "Generalized Algorithms for Constructing Statistical Language Models" pdf

Báo cáo khoa học: "Generalized Algorithms for Constructing Statistical Language Models" pdf

... algorithm for computing efficiently the expected counts of any sequence in a word lattice output by a speech recognizer or any arbitrary weighted automaton; describe a new technique for creating ... weight function; and the final weight function mapping to . A Weighted automaton is de- fined in a similar way by simply omitting the output la- bels. We denote by the set of strings accepted...
Ngày tải lên : 08/03/2014, 04:22
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Báo cáo khoa học: "Computer Backup for Field Work in Phonology" pdf

Báo cáo khoa học: "Computer Backup for Field Work in Phonology" pdf

... for Field Work in Phonology by Joseph E. Grimes, John R. Alsop, and Alan Wares, Summer Institute of Linguistics In the study of a previously unrecorded language, a taxonomy of the sound system ... phonological taxonomy is no longer by itself a final goal in linguistic analysis, a linguist who tries to study the phonology of a language without first mak- ing a good taxonomy stands as m...
Ngày tải lên : 16/03/2014, 19:20
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Báo cáo khoa học: "Reinforcement Learning for Mapping Instructions to Actions" pdf

Báo cáo khoa học: "Reinforcement Learning for Mapping Instructions to Actions" pdf

... relatively small in the dialogue management task, our state space is determined by the underlying environment and is typically quite large. We address this complexity by developing a policy gradient ... user. Reinforcement learning is applied very differ- ently in dialogue systems compared to our setup. In some respects, our task is more easily amenable to reinforcement learning. For instan...
Ngày tải lên : 17/03/2014, 01:20
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Báo cáo khoa học: "Statistical Models for Unsupervised Prepositional Phrase Attachment" pdf

Báo cáo khoa học: "Statistical Models for Unsupervised Prepositional Phrase Attachment" pdf

... While this form of attachment ambiguity is usually easy for people to resolve, a computer requires detailed knowledge about words (e.g., washed vs. bought) in order to successfully resolve ... the form (v, n,p, n2), in which both the noun n and verb v are always known. We therefore must use any information in the unambiguous cases to resolve the ambiguous cases. A natural wa...
Ngày tải lên : 17/03/2014, 07:20
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