Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
Báo cáo Y học: Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermine pdf
... Rapid caspase-dependent cell death in cultured human breast cancer cells induced by the polyamine analogue N1,N11-diethylnorspermineCecilia Hegardt1, Oskar T. Johannsson2and Stina ... t he cellular pools of putres-cine, spermidine and spermine by down-regulating the activity of the polyamine biosynthetic enzymes a nd up-regu-lating the activity of the catabolic enzyme spermidine/spermine ... transport of polyamines in and out of the cell also participates in keeping the polyamine pools a t an a ppropriate level f or the ongoingcellular activities. The function of the polyamines has...
- 7
- 326
- 0
Báo cáo y học: "980 nm diode lasers in oral and facial practice: current state of the science and art"
... the optimal in- docyanine green, to mark the hypochromic keratoses and angiomas in order to artificially increase their ability to absorb the Laser light. Innovative technologies such as the ... allowing excellent results to be obtained painlessly, in a short time and without requiring the patients to suspend their routines ac-tivities. For the operators, the main barriers to acquiring ... are capillary dilatations of the subpapillary plexus. Red or pink in colour, they have thin walls with endothelial cells and slight basal membrane. Angiomas may show parietal endothelial proliferation....
- 7
- 567
- 1
Báo cáo Y học: Regulation of glypican-1, syndecan-1 and syndecan-4 mRNAs expression by follicle-stimulating hormone, cAMP increase and calcium influx during rat Sertoli cell development pptx
... concentrations are inefficient in modifying Sertoli cell proteoglycan synthesis.Thus, the increase of intracellular calcium was appreci-ated indirectly by incubating Sertoli cell cultures with ... expression in Sertoli cells andother cell systems. In cultured Sertoli cells from 20-day-oldrats, verapamil and EGTA induced a sharp decrease in proteoglycan synthesis, affecting both secreted and cell- associated ... proteoglycans [53]. Intracellular calcium concen-tration either stimulates proteoglycan synthesis in bovinegranulosa cells [54,55] and in breast cancer cells [56] ordecreases proteoglycan synthesis...
- 9
- 342
- 0
Báo cáo khoa học: ERK and cell death: Mechanisms of ERK-induced cell death – apoptosis, autophagy and senescence doc
... ERK-mediated cell death: sustained and sequesteredactivityROS as mediators of ERK -induced cell death In the majority of the studies related to cell death induced by the Ras ⁄ Raf ⁄ ERK pathway, ERK ... of the injured cells without affecting neighbor-ing cells. The intrinsic pathway of apoptosis regu-lates the activity of the Bcl-2 family proteins thatcontrol the integrity of the mitochondrial ... cell death studies, the specificity of MEKinhibitors In many studies, implication of the Ras ⁄ Raf ⁄ ERKpathway in the induction of cell death is baseduniquely on the sole use of MEK1 ⁄ 2 inhibitorsPD05059...
- 20
- 393
- 0
Báo cáo khoa học: ERK and cell death: ERK1⁄2 in neuronal death Srinivasa Subramaniam1 and Klaus Unsicker2 pptx
... Molecular Embryology, Institute of Anatomy and Cell Biology, University of Freiburg, GermanyNeuronal death in the nervous systemNeuronal death is a major phenomenon in nervoussystem development ... the ERK1 ⁄ 2 pathway (PD98059) inhibitoronly [11]. In neuronal cells, glutamate- or camptothe-cin -induced neuronal injury was abolished whenERK1 ⁄ 2 activation was suppressed using U0126 inhibi-tor ... ERK1 ⁄ 2 in cell death, hippo-campal damage after traumatic brain injury was pre-vented by the inhibition of ERK1 ⁄ 2 by PD98059 [19].ERK1 ⁄ 2 activation is also implicated in hyperglycemia-mediated...
- 8
- 311
- 0
Báo cáo khoa học: ERK and cell death: ERK location and T cell selection pdf
... potentially harmful T cells are eliminated before they can fully develop. The shaping of the T cell repertoire begins whenimmature T cell precursors, called thymocytes, areselected by the ability of ... ofERK originating from the Golgi and leading to pERKbeing distributed throughout the cell (Fig. 1)[16,38,39]. The differences in the kinetics of pERKinduction may be explained by both the location ... that the subcellular localization pattern ofRas ⁄ MAPK determines the signaling output in a vari-ety of cell types (reviewed in [8]). Given the competingroles of ERK1 ⁄ 2 and JNK in determining...
- 9
- 350
- 0
Báo cáo khoa học: ERK and cell death: cadmium toxicity, sustained ERK activation and cell death pot
... brainmicrovascular endothelial cells (bEnd.3) [26], the human lymphoblastoid Boleth cell line [27] or the human promonocytic U-937 cell line [28]. A key point in explaining these discrepancies could ... thatcadmium -induced cell death resulted from disruptionof calcium homeostasis. Similarly, a rapid increase in ([Ca2+]cyt) is seen in mesangial cells exposed tocadmium. These cells die by autophagy ... directly inactivated by oxi-dation of cysteine thiols [38,39]. Therefore, the loss ofphosphatase activity is probably at least partly involved in the sustained activation of ERK following cadmiumpoisoning...
- 8
- 368
- 0
Báo cáo y học: "Clinical review: Medication errors in critical care"
... momentarily line up [71]. Therefore, it is notsurprising that models of quality improvement based onidentifying and removing ‘bad apple’ clinicians have not beeneffective in improving the safety of ... reportingbarriers partly owing to fewer liability concerns, and anopportunity to study recovery patterns [75]. Ideally, errorreporting should be voluntary, anonymous, centralized toincrease the ... Monitoring Study in Intensive Care) and the ICUSRS (Intensive Care Unit Safety Reporting System)have been developed with the goal of balancing the strengthsand limitations of error reporting [72].ConclusionPatient...
- 7
- 571
- 0
Báo cáo y học: "Mirror-Image Arachnoid Cysts in a Pair of Monozygotic Twins: A Case Report and Review of the Literature"
... younger age than the patients of the previous report. Consequently, our case is better in supporting a genetic origin in the pathogenesis of AC. The findings in our case indicate that early ... AC in the other twin (twin B), when the concerned parents took him to our department. Brain CT and MRI of twin B who did not have any com-plaints revealed a mirror-imaging of the AC in the ... neuroimaging is mandatory in the counterpart of the sympto-matic patient with AC, irrespective of the absence of symptoms. Key words: Mirror image, Arachnoid cyst, Monozygotic twins Introduction...
- 4
- 652
- 0
Báo cáo y học: "Can Occult Cystobiliary Fistulas in Hepatic Hydatid Disease Be Predicted Before Surgery"
... omentoplasty. In our external drainage procedure we input 2 drains in all cysts and before the inputting we explore for bili-ary yielding in the cyst and if we find a site of biliary coloring we ... detecting bile duct openings (21). In the present study, whether or not the pre-operative laboratory findings are indicators for occult CBC was determined. None of the laboratory findings ... parasitic infection which caused by echinicocus granulosus (1). It is an endemic disease in Turkey (2-4). In 50-70% of the patients, the liver is infected by the disease (5). Hepatic hydatid Ivyspring...
- 6
- 388
- 0
Từ khóa: báo cáo y họcbáo cáo y học cổ truyềnmẫu báo cáo y học cổ truyềnbao cao y hoc colchicinphan ban luan trong bao cao y hoc co truyenbáo cáo khoa học y họcNghiên cứu sự biến đổi một số cytokin ở bệnh nhân xơ cứng bì hệ thốngBáo cáo quy trình mua hàng CT CP Công Nghệ NPVNghiên cứu sự hình thành lớp bảo vệ và khả năng chống ăn mòn của thép bền thời tiết trong điều kiện khí hậu nhiệt đới việt namGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitGiáo án Sinh học 11 bài 13: Thực hành phát hiện diệp lục và carôtenôitĐỒ ÁN NGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWANNGHIÊN CỨU CÔNG NGHỆ KẾT NỐI VÔ TUYẾN CỰ LY XA, CÔNG SUẤT THẤP LPWAN SLIDEQuản lý hoạt động học tập của học sinh theo hướng phát triển kỹ năng học tập hợp tác tại các trường phổ thông dân tộc bán trú huyện ba chẽ, tỉnh quảng ninhTrả hồ sơ điều tra bổ sung đối với các tội xâm phạm sở hữu có tính chất chiếm đoạt theo pháp luật Tố tụng hình sự Việt Nam từ thực tiễn thành phố Hồ Chí Minh (Luận văn thạc sĩ)Phát triển du lịch bền vững trên cơ sở bảo vệ môi trường tự nhiên vịnh hạ longPhát hiện xâm nhập dựa trên thuật toán k meansNghiên cứu, xây dựng phần mềm smartscan và ứng dụng trong bảo vệ mạng máy tính chuyên dùngNghiên cứu tổng hợp các oxit hỗn hợp kích thƣớc nanomet ce 0 75 zr0 25o2 , ce 0 5 zr0 5o2 và khảo sát hoạt tính quang xúc tác của chúngNguyên tắc phân hóa trách nhiệm hình sự đối với người dưới 18 tuổi phạm tội trong pháp luật hình sự Việt Nam (Luận văn thạc sĩ)Giáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtGiáo án Sinh học 11 bài 14: Thực hành phát hiện hô hấp ở thực vậtChiến lược marketing tại ngân hàng Agribank chi nhánh Sài Gòn từ 2013-2015Đổi mới quản lý tài chính trong hoạt động khoa học xã hội trường hợp viện hàn lâm khoa học xã hội việt namHIỆU QUẢ CỦA MÔ HÌNH XỬ LÝ BÙN HOẠT TÍNH BẰNG KIỀM